ArticleeLight2022
Light-driven single-cell rotational adhesion frequency assay.
Article in eLight, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 44 citations in OpenAlex.
- Programmable rotation of single cells along arbitrary axes via opto-thermo-osmotic torque.Light, science & applications · 2026Article
- Impacts of particle morphology and rotation on optical manipulation.Light, science & applications · 2026Article
- Helical opto-thermoviscous flows drive out-of-plane rotation and particle spinning in a highly viscous micro-environment.Light, science & applications · 2026Article
- Tunable 3D optohydrodynamic torques from optical phase gradient-driven colloidal assemblies.Science advances · 2026Article
- Light-powered phagocytic macrophage microrobot (phagobot): both in vitro and in vivo.Light, science & applications · 2025Article
- Optical sorting: past, present and future.Light, science & applications · 2025Review
- Neural stimulation and modulation with sub-cellular precision by optomechanical bio-dart.Light, science & applications · 2024Article
- Dual-band dual-polarized sub-6 GHz phased array antenna with suppressed higher order modes.Scientific reports · 2024Article
- Light-controlled soft bio-microrobot.Light, science & applications · 2024Article
- 1 nm-Resolution Sorting of Sub-10 nm Nanoparticles Using a Dielectric Metasurface with Toroidal Responses.Small science · 2023Article
- Multimodal Optothermal Manipulations along Various Surfaces.ACS nano · 2023Article
- Review
- Optothermal rotation of micro-/nano-objects.Chemical communications (Cambridge, England) · 2023Review
- Article
- Creating stable trapping force and switchable optical torque with tunable phase of light.Science advances · 2022Article
- Light-driven high-precision cell adhesion kinetics.Light, science & applications · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
The interaction between cell surface receptors and extracellular ligands is highly related to many physiological processes in living systems. Many techniques have been developed to measure the ligand-receptor binding kinetics at the single-cell level. However, few techniques can measure the physiologically relevant shear binding affinity over a single cell in the clinical environment. Here, we develop a new optical technique, termed single-cell rotational adhesion frequency assay (scRAFA), that mimics in vivo cell adhesion to achieve label-free determination of both homogeneous and heterogeneous binding kinetics of targeted cells at the subcellular level. Moreover, the scRAFA is also applicable to analyze the binding affinities on a single cell in native human biofluids. With its superior performance and general applicability, scRAFA is expected to find applications in study of the spatial organization of cell surface receptors and diagnosis of infectious diseases. Supplementary Information: The online version contains supplementary material available at 10.1186/s43593-022-00020-4.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.