Evidence map›Paper›PMID 35965619›Full record

ArticleContrast media & molecular imaging2022

Study of PD-1 Customization and Autoimmune T Cells for Advanced Colorectal Cancer with High MSI Expression.

Na Li, Xiaojie Zhang, Yinsong Zhang, Fang Yang, Fengju Zhou

Open access · hybridAbstract read
In one paragraph

Article in Contrast media & molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Na LiHengshui City People's Hospital, Hengshui 053000, Hebei, China.ORCID 0000-0002-8761-0543
Xiaojie ZhangHengshui City People's Hospital, Hengshui 053000, Hebei, China.
Yinsong ZhangHengshui City People's Hospital, Hengshui 053000, Hebei, China.
Fang YangHengshui City People's Hospital, Hengshui 053000, Hebei, China.
Fengju ZhouHengshui City People's Hospital, Hengshui 053000, Hebei, China.
Hengshui University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the significance of PD-1 customization and autoimmune T-cell therapy for advanced colorectal cancer with high MSI expression. Methods: One hundred and eight patients with advanced colorectal cancer with high MSI expression admitted to our hospital between August 2019 and January 2022 were divided into control and study groups, and PD-1 customization and autoimmune T-cell therapy were administered to the two groups, respectively. Trends in immune indexes, PD-1 exposure, and survival rates were studied in both groups. Results: The treatment efficiency of the study group was 90.74%, which was higher than that of the control group (61.11%) ( Conclusion: PD-1 customization combined with autoimmune T-cell therapy is a novel therapeutic modality that can substantially improve.

Indexed as

Colorectal NeoplasmsMicrosatellite InstabilityB7-H1 AntigenHumansProgrammed Cell Death 1 ReceptorT-LymphocytesB7-H1 AntigenPDCD1 protein, humanProgrammed Cell Death 1 Receptor

Identifiers

PMID35965619
PMCPMC9357754
OpenAlexW4289077266

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.