ReviewFrontiers in oncology2022
Considerations for Upright Particle Therapy Patient Positioning and Associated Image Guidance.
Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Longitudinal CT number characterization of a novel upright CT for proton therapy planning.Journal of applied clinical medical physics · 2026Article
- Lung ion-fluoroscopy Guided Hadron therapy: LIGHT concept and proof-of-principle.Physics in medicine and biology · 2026Article
- Upright versus supine positioning for breast and lung radiotherapy: a pilot study on patient comfort, experience and lung function.Technical innovations & patient support in radiation oncology · 2026Article
- Machine Learning-Based Beam Delivery Time Model for Mevion S250i With Hyperscan Technology.International journal of particle therapy · 2026Article
- Upright and supine particle therapy of lung cancer: A 4D dosimetric comparison.Medical physics · 2026Article
- Towards ultra-fast treatments: large energy acceptance beam delivery systems and opportunities for proton beam therapy.Frontiers in oncology · 2026Review
- Automated Planning for Bias-Free Validation of Discrete Proton Arc Therapy for Oropharyngeal Cancer.International journal of particle therapy · 2025Article
- Assessment of upright immobilization methods for abdominal and head-and-neck cancer treatments in a carbon ion radiotherapy setting.Technical innovations & patient support in radiation oncology · 2025Article
- Comparison of cone beam computed tomography post-processing methods for online adaptive proton therapy of prostate cancer.Physics and imaging in radiation oncology · 2025Article
- Modeling and Validation of a Proton Therapy Couch Top.International journal of particle therapy · 2025Article
- Comparative analysis of residual setup errors in head and neck patients from upright versus supine radiotherapy postures.Medical physics · 2025Article
- HyperSHArc: Single-Isocenter Stereotactic Radiosurgery of Multiple Brain Metastases Using Proton, Helium, and Carbon Ion Arc Therapy.Advances in radiation oncology · 2025Article
- Transmission beam planning for improved robustness and efficiency in proton therapy for head and neck cancer.Physics and imaging in radiation oncology · 2025Article
- Pediatric CNS Radiation Oncology: Recent Developments and Novel Techniques.Current oncology (Toronto, Ont.) · 2025Review
- A radiation therapy platform to enable upright cone beam computed tomography and future upright treatment on existing photon therapy machines.Medical physics · 2025Article
- Current status and upcoming developments for online adaptive proton therapy enabling a closed feedback loop for near real-time adaptation.Frontiers in oncology · 2025Review
- First Dosimetric and Biological Verification for Spot-Scanning Hadron Arc Radiation Therapy With Carbon Ions.Advances in radiation oncology · 2024Article
- High-speed bioimpedance-based gating system for radiotherapy: Prototype and proof of principle.Journal of applied clinical medical physics · 2024Article
- A single-center experience of the upright proton therapy for skull-base chordomas and chondrosarcomas: Updated results.Clinical and translational radiation oncology · 2024Article
- Calculation method for novel upright CT scanner isodose curves.Journal of applied clinical medical physics · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Particle therapy is a rapidly growing field in cancer therapy. Worldwide, over 100 centers are in operation, and more are currently in construction phase. The interest in particle therapy is founded in the superior target dose conformity and healthy tissue sparing achievable through the particles' inverse depth dose profile. This physical advantage is, however, opposed by increased complexity and cost of particle therapy facilities. Particle therapy, especially with heavier ions, requires large and costly equipment to accelerate the particles to the desired treatment energy and steer the beam to the patient. A significant portion of the cost for a treatment facility is attributed to the gantry, used to enable different beam angles around the patient for optimal healthy tissue sparing. Instead of a gantry, a rotating chair positioning system paired with a fixed horizontal beam line presents a suitable cost-efficient alternative. Chair systems have been used already at the advent of particle therapy, but were soon dismissed due to increased setup uncertainty associated with the upright position stemming from the lack of dedicated image guidance systems. Recently, treatment chairs gained renewed interest due to the improvement in beam delivery, commercial availability of vertical patient CT imaging and improved image guidance systems to mitigate the problem of anatomical motion in seated treatments. In this review, economical and clinical reasons for an upright patient positioning system are discussed. Existing designs targeted for particle therapy are reviewed, and conclusions are drawn on the design and construction of chair systems and associated image guidance. Finally, the different aspects from literature are channeled into recommendations for potential upright treatment layouts, both for retrofitting and new facilities.
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