ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2022
Clinical and imaging features of diabetic striatopathy: report of 6 cases and literature review.
Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 12 citations in OpenAlex.
- Chorea Aggravated by Dehydration in a Patient With Diabetic Striatopathy: A Case Report.Brain & NeuroRehabilitation · 2026Article
- Article
- The diagnosis of diabetic striatopathy should be made only after careful exclusion of all possible differential diagnoses.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2026Article
- A Woman With Continuous, Involuntary, Unilateral Movement.Journal of the American College of Emergency Physicians open · 2025Review
- Diabetic Striatopathy as a Presenting Symptom in Newly Diagnosed Type 2 Diabetes Mellitus: A Case Report.Journal of the ASEAN Federation of Endocrine Societies · 2025Article
- Article
- Article
- Diabetic striatopathy in type 1 diabetes mellitus: a rare conundrum.BMJ case reports · 2023Article
- Cognitive decline as the main manifestation of diabetic striatal disease but without involuntary movements: a case report.BMC neurology · 2023Article
- Investigation of the factors associated with hemichorea/hemiballismus in post-stroke patients.Journal of neural transmission (Vienna, Austria : 1996) · 2023Article
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4 authors at 1 institution in 1 country.
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Abstract
objectiveTo explore the clinical manifestations, diagnosis, treatment, and pathogenesis of diabetic striatopathy (DS) to improve the understanding of the disease and avoid misdiagnosis or underdiagnosis.
methodsThe clinical, laboratory, and imaging data of 6 patients (5 Asian females and 1 Asian male) with diabetic striatum were analyzed retrospectively, and the related literature was reviewed.
resultsAll 6 patients showed hyperglycemia, 5 patients presented with involuntary movement of unilateral limbs, and 1 with unilateral limb numbness. Besides, 5 patients (except case 3) underwent MRI examinations that showed hyperintensity in unilateral caudate and lentiform nucleus on T1-weighted images. And all 6 patients who underwent brain CT examinations showed hyperdensity or isodensity in unilateral caudate and lentiform nucleus. None had a family history of similar abnormal movements. After blood glucose control and symptomatic support treatment, the symptoms of all patients improved to various degrees, and reexaminations showed that the lesions gradually disappeared.
conclusionDiabetic striatal disease is a rare complication of diabetes mellitus, the result of a combination of different pathogenesis. It is characterized by hyperglycemia, hemichorea, and contralateral striatal T1WI hyperintensity or CT hyperdensity. Both ketosis and nonketotic hyperglycemic hemichorea have typical imaging manifestations. The prognosis is excellent when this disease is detected early, and the lesions can be gradually absorbed and dissipated with glycemic control.
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