Evidence map›Paper›PMID 35965042›Full record

ReviewImmunology and allergy clinics of North America2022

Pathophysiology of Asthma-Chronic Obstructive Pulmonary Disease Overlap.

Andi Hudler, Fernando Holguin, Sunita Sharma

Open access · greenAbstract readReview
In one paragraph

Review in Immunology and allergy clinics of North America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. The miR-146a/Human mutation · 2026
    Article
  4. Review
  5. Observational
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Andi HudlerDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, 12700 East 19th Avenue, 9C03, Aurora, CO 80045, USA.
Fernando HolguinDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, 12700 East 19th Avenue, 9C03, Aurora, CO 80045, USA. Electronic address: Fernando.Holguin@cuanschutz.edu.
Sunita SharmaDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, 12700 East 19th Avenue, 9C03, Aurora, CO 80045, USA.
University of Colorado Anschutz Medical Campus · US

Funding

MULTIDISCIPLINARY RESPIRATORY DISEASES RESEARCH TRAININGT32HL007085 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ELLEN L BURNHAM, LISA A MAIER · 1985 to 2026
$21.6M
MICRORNAS AND EARLY LIFE EXPOSURES IN THE DEVELOPMENTAL ORIGIN OF ASTHMAR01HL125734 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI SHARMA, SUNITA · 2016 to 2020
$3.5M
NHLBI NIH HHS R01 HL125734NHLBI NIH HHS T32 HL007085
6 · The paper itself

Abstract

Asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) is a condition in which a person has clinical and biological features of both asthma and COPD. The pathophysiology behind the development of ACO is complex, with various inflammatory cells, cytokines, environmental factors, and architectural changes within the airways, all affecting a patient's clinical manifestation. A better understanding of the pathophysiologic mechanisms resulting in the development of ACO will help us to better identify potential drug targets and improve symptom burden and overall quality of life for patients living with ACO.

Indexed as

AsthmaPulmonary Disease, Chronic ObstructiveHumansQuality of LifeAsthmaAsthma-COPD overlapCOPDPathophysiology

Identifiers

PMID35965042
PMCPMC10355375
OpenAlexW4283716620

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.