Evidence map›Paper›PMID 35965007›Full record

ArticleMethods in enzymology2022

Attacking a DEAD problem: The role of DEAD-box ATPases in ribosome assembly and beyond.

Katrin Karbstein

Open access · greenAbstract read
In one paragraph

Article in Methods in enzymology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Effects ofExperimental and therapeutic medicine · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Katrin KarbsteinDepartment of Integrative Structural and Computational Biology, Scripps Florida, Jupiter, FL, United States; HHMI Faculty Scholar, Chevy Chase, MD, United States; The Skaggs Graduate School of Chemical and Biological Sciences, Scripps Florida, Jupiter, FL, United States. Electronic address: kkarbst@scripps.edu.
University of Montana · US

Funding

Dissecting the Mechanisms of Regulation and Quality Control in Ribosome Assembly and the Consequences of their FailureR35GM136323 · NIGMS · VANDERBILT UNIVERSITY · PI Katrin Karbstein · 2020 to 2026
$6.1M
Howard Hughes Medical Institute 55108536NIGMS NIH HHS R35 GM136323
6 · The paper itself

Abstract

DEAD-box proteins are a subfamily of ATPases with similarity to RecA-type helicases that are involved in all aspects of RNA Biology. Despite their potential to regulate these processes via their RNA-dependent ATPase activity, their roles remain poorly characterized. Here I describe a roadmap to study these proteins in the context of ribosome assembly, the process that utilizes more than half of all DEAD-box proteins encoded in the yeast genome.

Indexed as

Adenosine TriphosphatasesSaccharomyces cerevisiaeDEAD-box RNA HelicasesRibosomesRNAAdenosine TriphosphatasesDEAD-box RNA HelicasesRNADbp5Dbp7DEAD box protein rolesHas1Prp5Prpr28Rok1Sub2

Identifiers

PMID35965007
PMCPMC10154911
OpenAlexW4226296974

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.