ArticleSaudi medical journal2022
Radiological outcome of bone disease in multiple myeloma patients pre- and post therapy: A single center experience.
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Article in Saudi medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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13 authors at 4 institutions in 1 country.
Somaya A AljohaniFrom the Department of Internal Medicine (Aljohani, Alsalman, Ozair), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Nuclear Medicine (Saib, Syed), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Adult Hematology, Department of Oncology (Alhejazi, Alaskar, Gmati), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Biostatistics (Vishwakarm), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; and from the Clinical Trial Services (Mendoza), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
Israa H SaibFrom the Department of Internal Medicine (Aljohani, Alsalman, Ozair), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Nuclear Medicine (Saib, Syed), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Adult Hematology, Department of Oncology (Alhejazi, Alaskar, Gmati), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Biostatistics (Vishwakarm), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; and from the Clinical Trial Services (Mendoza), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
Ghulam Shah SyedFrom the Department of Internal Medicine (Aljohani, Alsalman, Ozair), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Nuclear Medicine (Saib, Syed), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Adult Hematology, Department of Oncology (Alhejazi, Alaskar, Gmati), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Biostatistics (Vishwakarm), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; and from the Clinical Trial Services (Mendoza), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
Ahmed AlruwailiFrom the Department of Internal Medicine (Aljohani, Alsalman, Ozair), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Nuclear Medicine (Saib, Syed), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Adult Hematology, Department of Oncology (Alhejazi, Alaskar, Gmati), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Biostatistics (Vishwakarm), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; and from the Clinical Trial Services (Mendoza), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
Shah P NumaniFrom the Department of Internal Medicine (Aljohani, Alsalman, Ozair), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Nuclear Medicine (Saib, Syed), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Adult Hematology, Department of Oncology (Alhejazi, Alaskar, Gmati), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Biostatistics (Vishwakarm), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; and from the Clinical Trial Services (Mendoza), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
Sulaiman A AlmuthriFrom the Department of Internal Medicine (Aljohani, Alsalman, Ozair), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Nuclear Medicine (Saib, Syed), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Adult Hematology, Department of Oncology (Alhejazi, Alaskar, Gmati), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Biostatistics (Vishwakarm), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; and from the Clinical Trial Services (Mendoza), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
Ramesh K VishwakarmFrom the Department of Internal Medicine (Aljohani, Alsalman, Ozair), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Nuclear Medicine (Saib, Syed), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Adult Hematology, Department of Oncology (Alhejazi, Alaskar, Gmati), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Biostatistics (Vishwakarm), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; and from the Clinical Trial Services (Mendoza), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
May Anne C MendozaFrom the Department of Internal Medicine (Aljohani, Alsalman, Ozair), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Nuclear Medicine (Saib, Syed), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Adult Hematology, Department of Oncology (Alhejazi, Alaskar, Gmati), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Biostatistics (Vishwakarm), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; and from the Clinical Trial Services (Mendoza), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
Mohammed J AlsalmanFrom the Department of Internal Medicine (Aljohani, Alsalman, Ozair), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Nuclear Medicine (Saib, Syed), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Adult Hematology, Department of Oncology (Alhejazi, Alaskar, Gmati), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Biostatistics (Vishwakarm), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; and from the Clinical Trial Services (Mendoza), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
Nabil M OzairFrom the Department of Internal Medicine (Aljohani, Alsalman, Ozair), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Nuclear Medicine (Saib, Syed), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Adult Hematology, Department of Oncology (Alhejazi, Alaskar, Gmati), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Biostatistics (Vishwakarm), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; and from the Clinical Trial Services (Mendoza), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
Ayman Y AlhejaziFrom the Department of Internal Medicine (Aljohani, Alsalman, Ozair), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Nuclear Medicine (Saib, Syed), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Adult Hematology, Department of Oncology (Alhejazi, Alaskar, Gmati), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Biostatistics (Vishwakarm), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; and from the Clinical Trial Services (Mendoza), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
Ahmed S AlaskarFrom the Department of Internal Medicine (Aljohani, Alsalman, Ozair), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Nuclear Medicine (Saib, Syed), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Adult Hematology, Department of Oncology (Alhejazi, Alaskar, Gmati), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Biostatistics (Vishwakarm), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; and from the Clinical Trial Services (Mendoza), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
Giamal E GmatiFrom the Department of Internal Medicine (Aljohani, Alsalman, Ozair), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Nuclear Medicine (Saib, Syed), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Adult Hematology, Department of Oncology (Alhejazi, Alaskar, Gmati), King Abdulaziz Medical City Ministry of National Guard - Health Affairs, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; from the Department of Biostatistics (Vishwakarm), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences; and from the Clinical Trial Services (Mendoza), King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
King Abdullah International Medical Research Center · SAKing Saud bin Abdulaziz University for Health Sciences · SANational Guard Health Affairs · SAKing Abdulaziz Medical City · SA
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo find any correlation between the clinical response as per International Working Myeloma Group (IWMG) response criteria and the radiological response at the end of treatment.
methodsA retrospective cohort study was conducted, total of 39 patients whom diagnosed with multiple myeloma (MM) between January 2010 and December 2018 and fulfilled the study criteria were included.
resultsThe high sensitivity and specificity of positron emission tomography/computed tomography (PET/CT) in detecting osteolytic myeloma lesions in the bones was strongly emphasized in our study. Follow up PET/CT, we found that while 17 patients showed complete remission in PET/CT, and 14 of these of patients demonstrated a complete clinical response at end of therapy assessment.
conclusionAlthough we did not find a statistically significant correlation between the response versus metabolic activity and the number of bone/bone marrow lesions, however, our study was limited by the absence of clear criteria for defining disease response in PET/CT in MM patients. Further prospective analysis would be needed to establish a defined criterion.
Indexed as
Bone DiseasesMultiple MyelomaFluorodeoxyglucose F18HumansPositron-Emission TomographyPositron Emission Tomography Computed TomographyRetrospective StudiesFluorodeoxyglucose F18bone diseasemultiple myelomaoutcomePET scan
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