Evidence map›Paper›PMID 35964000›Full record

ArticleBMC geriatrics2022

Protocol for a randomized controlled trial of mindfulness-based stress reduction to improve attentional control in older adults (HealthyAgers trial).

Ruchika Shaurya Prakash, Stephanie Fountain-Zaragoza, Megan Fisher, Oyetunde Gbadeyan, Rebecca Andridge, Janice Kiecolt-Glaser, Heena R Manglani, Elizabeth J Duraney, Anita Shankar, Michael R McKenna and 3 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03626532 (Mind-body Interventions for Healthy Aging), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03626532 nacompletednot on this map

Mind-body Interventions for Healthy Aging

TypeinterventionalSponsorOhio State UniversityRan2018 to 2023Enrolled173ConditionsAgingArmsMindfulness-Based Stress Reduction (MBSR), Lifestyle Education (LifeEd)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Psychosocial Correlates of Adherence to Mind-Body Interventions.Prevention science : the official journal of the Society for Prevention Research · 2025
    Trial
  3. Trial
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Ruchika Shaurya PrakashDepartment of Psychology, The Ohio State University, 62 Psychology Building, 1835 Neil Avenue, Columbus, OH, 43210, USA. prakash.30@osu.edu.ORCID 0000-0002-2224-6242
Stephanie Fountain-ZaragozaDepartment of Psychology, The Ohio State University, 62 Psychology Building, 1835 Neil Avenue, Columbus, OH, 43210, USA.
Megan FisherDepartment of Psychology, The Ohio State University, 62 Psychology Building, 1835 Neil Avenue, Columbus, OH, 43210, USA.
Oyetunde GbadeyanDepartment of Psychology, The Ohio State University, 62 Psychology Building, 1835 Neil Avenue, Columbus, OH, 43210, USA.
Rebecca AndridgeDepartment of Biostatistics, The Ohio State University, Columbus, OH, USA.
Janice Kiecolt-GlaserInstitute of Behavioral Medicine Research, Wexner Medical Center, Columbus, OH, USA.
Heena R ManglaniDepartment of Psychology, The Ohio State University, 62 Psychology Building, 1835 Neil Avenue, Columbus, OH, 43210, USA.
Elizabeth J DuraneyDepartment of Psychology, The Ohio State University, 62 Psychology Building, 1835 Neil Avenue, Columbus, OH, 43210, USA.
Anita ShankarDepartment of Psychology, The Ohio State University, 62 Psychology Building, 1835 Neil Avenue, Columbus, OH, 43210, USA.
Michael R McKennaDepartment of Psychology, The Ohio State University, 62 Psychology Building, 1835 Neil Avenue, Columbus, OH, 43210, USA.
James TengDepartment of Psychology, The Ohio State University, 62 Psychology Building, 1835 Neil Avenue, Columbus, OH, 43210, USA.
Madhura PhansikarDepartment of Psychology, The Ohio State University, 62 Psychology Building, 1835 Neil Avenue, Columbus, OH, 43210, USA.
Rosie CanterDepartment of Psychology, The Ohio State University, 62 Psychology Building, 1835 Neil Avenue, Columbus, OH, 43210, USA.
The Ohio State University · USMedical University of South Carolina · USThe Ohio State University Wexner Medical Center · US

Funding

Research Training in Complementary and Integrative MedicineT32AT000051 · NCCIH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI GLORIA Y YEH · 1999 to 2026
$10.2M
Mindfulness Training for Mitigating Age-Related Cognitive Decline in the ElderlyR01AG054427 · NIA · OHIO STATE UNIVERSITY · PI PRAKASH, RUCHIKA SHAURYA · 2017 to 2021
$2.2M
NCCIH NIH HHS T32 AT000051NIA NIH HHS R01 AG054427
6 · The paper itself

Abstract

backgroundMindfulness meditation is a form of mind-body intervention that has increasing scientific support for its ability to reduce age-related declines in cognitive functioning, improve affective health, and strengthen the neural circuitry supporting improved cognitive and affective health. However, the majority of existent studies have been pilot investigations with small sample sizes, limited follow-up data, and a lack of attention to expectancy effects. Here, we present the study design of a Phase I/II, efficacy trial-HealthyAgers trial-that examines the benefits of a manualized mindfulness-based stress reduction program in improving attentional control and reducing mind-wandering in older adults.

methodsOne hundred fifty older adults (ages 65-85 years) will be randomized into one of two groups: an eight-week mindfulness program or an eight-week, placebo-controlled, lifestyle education program. Behavioral and neuroimaging assessments are conducted before and after the training. Participants are then invited to booster sessions once every three months for a period of 12 months with post-intervention follow-up assessments conducted at 6-months and 12-months. The primary outcomes for the study are behavioral measures of attentional control and mind-wandering. Additional, secondary outcomes include network strength in an a priori defined neuromarker of attentional control, fluid and everyday cognition, emotion regulation strategy use, and markers of inflammation. DISCUSSION: This study will establish the efficacy of a group-based, low-cost mind-body intervention for the inter-related facets of attentional control and mind-wandering in older adults. Strengths of this study include a well-designed, placebo-controlled comparison group, use of web/mobile application to track study adherence, and longitudinal follow-up.

trial registrationClinicaltrials.gov (# NCT03626532 ). Registered August 4, 2018.

Indexed as

AttentionMindfulnessStress, PsychologicalAgedAged, 80 and overClinical Trials, Phase I as TopicClinical Trials, Phase II as TopicHumansRandomized Controlled Trials as TopicResearch DesignAttentional controlHealthy agingMindfulnessMind-wandering

Identifiers

PMID35964000
PMCPMC9375078
OpenAlexW4291168017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.