Evidence map›Paper›PMID 35963984›Full record

ArticleJournal of molecular neuroscience : MN2022

The Effects of Methanol Extracts of Hyssopus officinalis on Model of Induced Glioblastoma Multiforme (GBM) in Rats.

Sepideh Khaksar, Khadijeh Kiarostami, Shahrzad Alinaghi

Abstract read
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In one paragraph

Article in Journal of molecular neuroscience : MN, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Pharmacophylogenetic relationships of genusFrontiers in pharmacology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sepideh KhaksarDepartment of Plant Sciences, Faculty of Biological Sciences, Alzahra University, Tehran, Iran. s.khaksar@alzahra.ac.ir.ORCID http://orcid.org/0000-0003-2251-7329
Khadijeh KiarostamiDepartment of Plant Sciences, Faculty of Biological Sciences, Alzahra University, Tehran, Iran.ORCID http://orcid.org/0000-0002-2786-0188
Shahrzad AlinaghiDepartment of Plant Sciences, Faculty of Biological Sciences, Alzahra University, Tehran, Iran.
Alzahra University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the complexity of pathophysiological processes of brain tumors, ineffective therapies, and high mortality rate, new therapeutic options with less toxicity are necessary. Hyssopus officinalis (hyssop) is an aromatic plant with important biological activities. The aim of this study is to assess the anti-cancer effect of hyssop extract on damages of glioblastoma multiforme. In this study, total flavonoids, phenolic content, and quantification of phenolic compound of hyssop extracts were analyzed. In vitro antioxidant properties of hyssop extract were also examined. In addition, cell viability, apoptosis, and cell cycle were evaluated in C6 glioma cell culture. In vivo, the rats were divided randomly into four main groups: intact, control, vehicle, and treatment groups. 1 × 10

Indexed as

Brain NeoplasmsGlioblastomaAnimalsAntioxidantsHyssopus PlantMethanolPlant ExtractsRatsRNA, MessengerSuperoxide DismutaseTumor Suppressor Protein p53Vascular Endothelial Growth Factor AAntioxidantsMethanolPlant ExtractsRNA, MessengerSuperoxide DismutaseTumor Suppressor Protein p53Vascular Endothelial Growth Factor AAntioxidant enzymesApoptotic cellsBrain tumorCell cycleCell viabilityHyssopus officinalisp21p53Tumor volumeVEGF

Identifiers

PMID35963984
OpenAlexW4291396219

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.