Evidence map›Paper›PMID 35963624›Full record

ReviewEndocrinology and metabolism clinics of North America2022

Lipoprotein Assessment in the twenty-first Century.

Diego Lucero, Anna Wolska, Zahra Aligabi, Sarah Turecamo, Alan T Remaley

Open access · greenAbstract readReview
In one paragraph

Review in Endocrinology and metabolism clinics of North America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Alterations in the lipid profile in acne vulgaris patients: A meta-analysis.The Journal of international medical research · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Deciphering Acute Coronary Syndromes Pathobiology Through Proteomics.Journal of cardiovascular development and disease · 2025
    Review
  6. Article
  7. Molecular Regulation and Therapeutic Targeting of VLDL Production in Cardiometabolic Disease.Cellular and molecular gastroenterology and hepatology · 2025
    Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Diego LuceroLipoprotein Metabolism Laboratory, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, 9000 Rockville Pike, Building 10, Room 5D09, Bethesda, MD 20892, USA. Electronic address: diego.lucero3@nih.gov.
Anna WolskaHeart Disease Phenomics Laboratory, Epidemiology and Community Health Branch, National Heart, Lung, and Blood Institute. National Institutes of Health, 9000 Rockville Pike, Building 10, Room 5N323, Bethesda, MD 20892, USA.
Zahra AligabiLipoprotein Metabolism Laboratory, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, 9000 Rockville Pike, Building 10, Room 5D09, Bethesda, MD 20892, USA.
Sarah TurecamoHeart Disease Phenomics Laboratory, Epidemiology and Community Health Branch, National Heart, Lung, and Blood Institute. National Institutes of Health, 9000 Rockville Pike, Building 10, Room 5N323, Bethesda, MD 20892, USA.
Alan T RemaleyLipoprotein Metabolism Laboratory, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, 9000 Rockville Pike, Building 10, Room 5D09, Bethesda, MD 20892, USA.
National Institutes of Health · USNational Heart Lung and Blood Institute · US

Funding

Development and assessment of cardiovascular risk biomarkersZIAHL006275 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI REMALEY, ALAN THOMAS · 2022 to 2025
$6.0M
Intramural NIH HHS Z99 HL999999
6 · The paper itself

Abstract

Based on decades of both basic science and epidemiologic research, there is overwhelming evidence for the causal relationship between high levels of cholesterol, especially low-density lipoprotein cholesterol and cardiovascular disease. Risk evaluation and monitoring the response to lipid-lowering therapies are heavily dependent on the accurate assessment of plasma lipoproteins in the clinical laboratory. This article provides an update of lipoprotein metabolism as it relates to atherosclerosis and how diagnostic measures of lipids and lipoproteins can serve as markers of cardiovascular risk, with a focus on recent advances in cardiovascular risk marker testing.

Indexed as

AtherosclerosisCardiovascular DiseasesBiomarkersCholesterolCholesterol, LDLHumansLipoproteinsBiomarkersCholesterolCholesterol, LDLLipoproteinsAdvanced lipoprotein testingCardiovascular risk assessmentHDL functionalityLDL-C calculationLipoprotein (a)Lipoprotein diagnostic assaysNon-HDL cholesterolRecommendations for lipoprotein assessment

Identifiers

PMID35963624
PMCPMC9382697
OpenAlexW4284969082

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.