Evidence map›Paper›PMID 35963238›Full record

ArticleNeuron2022

Task specificity in mouse parietal cortex.

Julie J Lee, Michael Krumin, Kenneth D Harris, Matteo Carandini

Abstract read
In one paragraph

Article in Neuron, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Integration of learned artificial sensation with vision during freely moving navigation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
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  6. Parietal cortex is causally required for state-dependent decisions.bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
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  10. Article
  11. Review
  12. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julie J LeeUCL Institute of Ophthalmology, University College London, Gower Street, London WC1E 6AE, UK. Electronic address: juliejlee@nyu.edu.
Michael KruminUCL Institute of Ophthalmology, University College London, Gower Street, London WC1E 6AE, UK.
Kenneth D HarrisUCL Queen Square Institute of Neurology, University College London, Gower Street, London WC1E 6AE, UK.
Matteo CarandiniUCL Institute of Ophthalmology, University College London, Gower Street, London WC1E 6AE, UK.

Funding

Wellcome Trust 109004Wellcome Trust 205093Wellcome Trust 205093/Z/16/ZWellcome Trust 223144
6 · The paper itself

Abstract

Parietal cortex is implicated in a variety of behavioral processes, but it is unknown whether and how its individual neurons participate in multiple tasks. We trained head-fixed mice to perform two visual decision tasks involving a steering wheel or a virtual T-maze and recorded from the same parietal neurons during these two tasks. Neurons that were active during the T-maze task were typically inactive during the steering-wheel task and vice versa. Recording from the same neurons in the same apparatus without task stimuli yielded the same specificity as in the task, suggesting that task specificity depends on physical context. To confirm this, we trained some mice in a third task combining the steering wheel context with the visual environment of the T-maze. This hybrid task engaged the same neurons as those engaged in the steering-wheel task. Thus, participation by neurons in mouse parietal cortex is task specific, and this specificity is determined by physical context.

Indexed as

NeuronsParietal LobeAnimalsMacaca mulattaMicecerebral cortexdecision-makingsensorimotor processing

Identifiers

PMID35963238
PMCPMC9616730

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.