Evidence map›Paper›PMID 35963024›Full record

ArticleJournal of psychiatric research2022

Examining the associations between PTSD symptom clusters and alcohol-related problems in a sample of low-SES treatment-seeking Black/African American adults.

Ian C Fischer, Melanie E Bennett, Robert H Pietrzak, Brian C Kok, Daniel J O Roche

Open access · greenAbstract read
In one paragraph

Article in Journal of psychiatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Ian C FischerIndiana University-Purdue University at Indianapolis (IUPUI), Indianapolis, IN, USA; VA Maryland Health Care System, Baltimore, MD, USA.
Melanie E BennettVA Maryland Health Care System, Baltimore, MD, USA; Department of Psychiatry, University of Maryland, Baltimore, Baltimore, MD, USA; VA VISN 5 Mental Illness Research, Education and Clinical Center, Baltimore VA Medical Center, Baltimore, MD, USA.
Robert H PietrzakU.S. Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, VA Connecticut Healthcare System, West Haven, CT, USA; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA; Department of Social and Behavioral Sciences, Yale School of Public Health, New Haven, CT, USA.
Brian C KokVA Maryland Health Care System, Baltimore, MD, USA.
Daniel J O RocheDepartment of Psychiatry, University of Maryland, Baltimore, Baltimore, MD, USA. Electronic address: droche@som.umaryland.edu.
University of Maryland, Baltimore · USUnited States Department of Veterans Affairs · USUniversity of Indianapolis · USVA Maryland Health Care System · US

Funding

Pharmacogenetic Treatment with Anti-Glutaminergic Agents for Comorbid PTSD & AUDR01AA024760 · NIAAA · UNIVERSITY OF MARYLAND BALTIMORE · PI BENNETT, MELANIE E. · 2016 to 2020
$3.0M
Development of minocycline as a neuroimmune therapy for alcohol use disorderK01AA026005 · NIAAA · UNIVERSITY OF MARYLAND BALTIMORE · PI ROCHE, DANIEL · 2017 to 2021
$925k
NIAAA NIH HHS K01 AA026005NIAAA NIH HHS R01 AA024760
6 · The paper itself

Abstract

Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) often co-occur. This comorbidity negatively influences treatment outcomes, functioning, and quality of life. To better understand the relation between PTSD and AUD, research has begun to examine the influence of PTSD symptom clusters on alcohol-related problems. The current study is the first to analyze the associations between PTSD symptom clusters and alcohol consumption and AUD symptom severity in a treatment-seeking sample of Black/African American (AA) adults with co-occurring AUD and PTSD symptoms. Examination of these associations may help to facilitate greater recovery in this underserved population by identifying more precise targets for treatment. PTSD symptom clusters were identified from both the current 4-factor model identified in the DSM-5 and from a recently proposed 7-factor model. Participants were Black/AA adults (50.6% male) who endorsed trauma exposure and were seeking treatment for alcohol misuse. The majority (66%) were unemployed and almost half (45%) reported an income at or lower than $20,000. In the 4-factor model, results showed Cluster D symptoms of PTSD (i.e., negative alterations in cognitions and mood) were independently associated with alcohol consequences. Use of the 7-factor model, which divides Cluster D into symptoms of negative affect and anhedonia, further demonstrated that only anhedonic symptoms were independently associated with alcohol consequences. No symptom clusters were uniquely associated with alcohol consumption. Results suggest the absence of positive emotions, rather than the presence of negative emotions, are primarily associated with alcohol-related problems in a sample of trauma-exposed, Black/AA adults seeking treatment for alcohol misuse.

Indexed as

AlcoholismAlcohol-Related DisordersStress Disorders, Post-TraumaticAdultBlack or African AmericanFemaleHumansMaleQuality of LifeSyndromeAfrican-AmericanAlcohol use disorderPosttraumatic stress disorderSymptom clustersTreatment-seeking

Identifiers

PMID35963024
PMCPMC9481727
OpenAlexW4289767346

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.