Evidence map›Paper›PMID 35962838›Full record

ArticleInsights into imaging2022

Cost-effectiveness of the implementation of [

Esmée C A van der Sar, Willem R Keusters, Ludwike W M van Kalmthout, Arthur J A T Braat, Bart de Keizer, Geert W J Frederix, Anko Kooistra, Jules Lavalaye, Marnix G E H Lam, Harm H E van Melick

Abstract read
In one paragraph

Article in Insights into imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Assessing Value for Money in Theranostic Nuclear Medicine: A Systematic Review.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Comparative Performance ofDiagnostics (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Diagnostic performance ofOncology letters · 2024
    Article
  8. Review
  9. Recent nanotheranostic approaches in cancer research.Clinical and experimental medicine · 2024
    Review
  10. Why does PSMA PET improve quality of life?European journal of nuclear medicine and molecular imaging · 2023
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Esmée C A van der Sar *Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands. e.c.a.vandersar@umcutrecht.nl.ORCID http://orcid.org/0000-0003-4406-2409
Willem R Keusters *Julius Center, University Medical Center Utrecht, Utrecht, The Netherlands.
Ludwike W M van KalmthoutDepartment of Radiotherapy, University Medical Center Utrecht, Utrecht, The Netherlands.
Arthur J A T BraatDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
Bart de KeizerDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
Geert W J FrederixJulius Center, University Medical Center Utrecht, Utrecht, The Netherlands.
Anko KooistraDepartment of Urology, Meander Medical Center, Amersfoort, The Netherlands.
Jules LavalayeDepartment of Nuclear Medicine, St Antonius Hospital, Nieuwegein, The Netherlands.
Marnix G E H LamDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
Harm H E van MelickDepartment of Urology, St Antonius Hospital, Nieuwegein, The Netherlands.

Funding

KWF Kankerbestrijding 11399/2017-2
6 · The paper itself

Abstract

backgroundDespite its high specificity, PSMA PET/CT has a moderate to low sensitivity of 40-50% for pelvic lymph node detection, implicating that a negative PSMA PET/CT cannot rule out lymph node metastases. This study investigates a strategy of implementing PSMA PET/CT for initial prostate cancer staging and treatment planning compared to conventional diagnostics. In this PSMA PET/CT strategy, a bilateral extended pelvic lymph node dissection (ePLND) is only performed in case of a negative PSMA PET/CT; in case of a positive scan treatment planning is solely based on PSMA PET/CT results.

methodA decision table and lifetime state transition model were created. Quality-adjusted life years and health care costs were modelled over lifetime.

resultsThe PSMA PET/CT strategy of treatment planning based on initial staging with [

conclusionInitial staging and treatment planning based on [

Indexed as

Cost-effectivenessGalliumProstate cancerPSMA PET/CTRadioligand

Identifiers

PMID35962838
PMCPMC9375809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.