Evidence map›Paper›PMID 35962531›Full record

ArticlePhotochemistry and photobiology2023

Moderate Low UVB Irradiation Modulates Tumor-associated Macrophages and Dendritic Cells and Promotes Antitumor Immunity in Tumor-bearing Mice.

Gayoung Park, Yan-Hong Cui, Seungwon Yang, Ming Sun, Emma Wilkinson, Haixia Li, Yuhan Blair Zhang, Jing Chen, Marc Bissonnette, Wenbin Lin and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Photochemistry and photobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Gayoung Park *Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL.
Yan-Hong Cui *Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL.
Seungwon Yang *Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL.
Ming SunDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL.
Emma WilkinsonDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL.
Haixia LiDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL.
Yuhan Blair ZhangDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL.
Jing ChenDepartment of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL.
Marc BissonnetteDepartment of Medicine, Section of Gastroenterology, Hepatology & Nutrition, University of Chicago, Chicago, IL.
Wenbin LinDepartment of Chemistry, University of Chicago, Chicago, IL.
Yu-Ying HeDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL.ORCID 0000-0002-2665-7962
University of Chicago · USUniversity of Illinois Chicago · US

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI MARK W. LINGEN · 1985 to 2026
$122.1M
Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6M
YTHDF2 and UVB damage response in skin cancerR01ES024373 · NIEHS · UNIVERSITY OF CHICAGO · PI HE, YU-YING · 2015 to 2023
$4.3M
The mechanistic role of METTL14 in UVB-induced skin tumorigenesisR01ES030576 · NIEHS · UNIVERSITY OF CHICAGO · PI HE, YU-YING · 2019 to 2023
$3.0M
FTO and RNA methylation in arsenic tumorigenicityR01ES031534 · NIEHS · UNIVERSITY OF CHICAGO · PI HE, YU-YING · 2020 to 2022
$1.2M
NCATS NIH HHS UL1 TR000430NCI NIH HHS P30 CA014599NIEHS NIH HHS P30 ES027792NIEHS NIH HHS R01 ES024373NIEHS NIH HHS R01 ES030576NIEHS NIH HHS R01 ES031534
6 · The paper itself

Abstract

Excessive, high doses of ultraviolet B (UVB) UVB irradiation are known to cause skin cancer, aging and immunosuppression. On the contrary, moderate low doses of UVB irradiation are shown to be essential and beneficial to human health, including a tumor-suppressive effect. However, the mechanism by which low levels of UVB suppress tumorigenesis remains unclear. Here, using tumor-bearing mouse models, we show that moderate low repetitive UVB irradiation increases the percentage of activated CD4

Indexed as

CD8-Positive T-LymphocytesSkin NeoplasmsAnimalsDendritic CellsHumansMiceTumor-Associated MacrophagesUltraviolet Rays

Identifiers

PMID35962531
PMCPMC9884319
OpenAlexW4288689704

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.