Evidence map›Paper›PMID 35962464›Full record

ArticleJournal of neuroimaging : official journal of the American Society of Neuroimaging2022

Comparison of axial and sagittal spinal cord motion measurements in degenerative cervical myelopathy.

Nikolai Pfender, Jan Rosner, Carl Moritz Zipser, Susanne Friedl, Kevin Vallotton, Reto Sutter, Markus Klarhoefer, Martin Schubert, Michael Betz, José Miguel Spirig and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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  5. Comparison of axial and sagittal spinal cord motion measurements in degenerative cervical myelopathy.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Nikolai PfenderSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Jan RosnerSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Carl Moritz ZipserSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Susanne FriedlSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Kevin VallottonSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Reto SutterRadiology, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Markus KlarhoeferSiemens Healthcare AG, Zürich, Switzerland.
Martin SchubertSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Michael BetzUniversity Spine Centre Zurich, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
José Miguel SpirigUniversity Spine Centre Zurich, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Maryam SeifSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Michèle HubliSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Patrick FreundSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Mazda FarshadUniversity Spine Centre Zurich, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Armin CurtSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Markus HuppSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.ORCID 0000-0003-0845-2514
University of Zurich · CHSiemens (Switzerland) · CHUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe timing of decision-making for a surgical intervention in patients with mild degenerative cervical myelopathy (DCM) is challenging. Spinal cord motion phase contrast MRI (PC-MRI) measurements can reveal the extent of dynamic mechanical strain on the spinal cord to potentially identify high-risk patients. This study aims to determine the comparability of axial and sagittal PC-MRI measurements of spinal cord motion with the prospect of improving the clinical workup.

methodsSixty-four DCM patients underwent a PC-MRI scan assessing spinal cord motion. The agreement of axial and sagittal measurements was determined by means of intraclass correlation coefficients (ICCs) and Bland-Altman analyses.

resultsThe comparability of axial and sagittal PC-MRI measurements was good to excellent at all cervical levels (ICCs motion amplitude: .810-.940; p < .001). Significant differences between axial and sagittal amplitude values could be found at segments C3 and C4, while its magnitude was low (C3: 0.07 ± 0.19 cm/second; C4: -0.12 ± 0.30 cm/second). Bland-Altman analysis showed a good agreement between axial and sagittal PC-MRI scans (coefficients of repeatability: minimum -0.23 cm/second at C2; maximum -0.58 cm/second at C4). Subgroup analysis regarding anatomic conditions (stenotic vs. nonstenotic segments) and different velocity encoding (2 vs. 3 cm/second) showed comparable results.

conclusionsThis study demonstrates good comparability between axial and sagittal spinal cord motion measurements in DCM patients. To this end, axial and sagittal PC-MRI are both accurate and sensitive in detecting pathologic cord motion. Therefore, such measures could identify high-risk patients and improve clinical decision-making (ie, timing of decompression).

Indexed as

Spinal Cord CompressionSpinal Cord DiseasesCervical VertebraeHumansMagnetic Resonance ImagingNeckSpinal Cordcervical stenosisdegenerative cervical myelopathyphase contrast MRIspinal cord compressionspinal cord motionspinal cord oscillation

Identifiers

PMID35962464
PMCPMC9805009
OpenAlexW4291676847

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.