ArticleBMC pediatrics2022
Large scale application of pulse oximeter and auscultation in screening of neonatal congenital heart disease.
Article in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07542509 (Digital diagnoSis of Cardiac sOUNd in peDiatric Patients [DI-SOUND Study]), which is not on this map. Cited by 14 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Digital diagnoSis of Cardiac sOUNd in peDiatric Patients [DI-SOUND Study]
Who cites it
14 citing papers in PubMed, 18 citations in OpenAlex.
- Rational and design of the digital diagnosis of cardiac sounds in paediatric patients (DI_SOUND) study.European heart journal. Digital health · 2026Article
- Article
- [Expert consensus on the diagnosis and treatment of common neonatal diseases in primary healthcare institutions: congenital heart disease (2025)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Article
- Utility of the joint index in newborn congenital heart disease screening.Scientific reports · 2025Article
- Nationwide Survey on Neonatal Critical Congenital Cardiopathies in Mexico: Data from 76 Public Health Service Hospital Units.International journal of neonatal screening · 2025Article
- Prediction of significant congenital heart disease in infants and children using continuous wavelet transform and deep convolutional neural network with 12-lead electrocardiogram.BMC pediatrics · 2025Article
- Prospective Evaluation of Pulse Oximetry Screening for Critical Congenital Heart Disease in a Jordanian Tertiary Hospital: High Incidence and Early Detection Challenges.Pediatric reports · 2025Article
- Recent Advances in the Wearable Devices for Monitoring and Management of Heart Failure.Reviews in cardiovascular medicine · 2024Review
- Segmentation of Heart Sound Signal Based on Multi-Scale Feature Fusion and Multi-Classification of Congenital Heart Disease.Bioengineering (Basel, Switzerland) · 2024Article
- Article
- Accurately assessing congenital heart disease using artificial intelligence.PeerJ. Computer science · 2024Article
- Diagnostic Accuracy of Physical Examination and Pulse Oximetry for Critical Congenital Cardiac Disease Screening in Newborns.Children (Basel, Switzerland) · 2023Review
- The 'Ironclad friendship' of China-Cambodia, lays the first step in the foundation of early diagnosis and treatment of asymptomatic congenital heart Defects- A multi-national screening and intervention project, 2017-2020.BMC cardiovascular disorders · 2023Article
- Role of artificial intelligence in early detection of congenital heart diseases in neonates.Frontiers in digital health · 2023Review
Corrections and comments
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Authors and funding
15 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo conduct a retrospective evaluation of a large clinical implementation of combined pulse oximeter (POX) and cardiac auscultation as a fast-screening device for congenital heart disease (CHD).
methodsEvery newborn in a large maternity healthcare center received auscultation and POX screening within 24 hours after delivery. When an abnormal heart murmur or SpO
resultsFrom January 1, 2018 to December 31, 2019, there were 44,147 livebirths at the studied hospital where 498 suspected CHD were identified: 27 newborns by POX screening and 471 by cardiac auscultation. The diagnosis was further confirmed in 458 neonates through echocardiogram. This result put forth an overall diagnosis rate of 92.0%. Cardiac auscultation detected the majority of CHD cases 438 (95.6%) while POX only screened 20 (4.4%) cases. Interestingly, no CHD case was detected by both auscultation examination and POX screening. Auscultation detected most of the common types of CHD, but POX excelled in identifying rare and critical cases. POX screening alone had a very low accuracy of 74.07% in positive predict value (PPV). On the other hand, auscultation functioned well in terms of PPV and negative predict value (NPV) (92.99 and 99.95%, respectively), but the addition of POX improved the overall screening performance resulting in 100% NPV. We also validate the finding with the data 6 months after the study period.
conclusionOur study demonstrated that addition of pulse oximetry to routine cardiac auscultation could be used as an accurate and feasible screening for early screening of CHD in newborns in large-scale clinical practice.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.