Evidence map›Paper›PMID 35962378›Full record

ArticleBMC psychiatry2022

Validation of brief screening instruments for internalizing and externalizing disorders in Mozambican adolescents.

Kathryn L Lovero, Salma Ebrahim Adam, Carolina Ezequias Bila, Elda D Canda, Maria Eduarda Fernandes, Teresa I Baltazar Rodrigues, Mariel C Tai Sander, Claude A Mellins, Cristiane S Duarte, Palmira Fortunato Dos Santos and 1 more

Abstract read
In one paragraph

Article in BMC psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kathryn L LoveroDepartment of Sociomedical Sciences, Columbia University Mailman School of Public Health, 722 W. 168th St. 9th Floor, New York, NY, 10032, USA. kll2153@cumc.columbia.edu.
Salma Ebrahim AdamDepartment of Mental Health, Ministry of Health, Maputo, Mozambique.
Carolina Ezequias BilaDepartment of Mental Health, Ministry of Health, Maputo, Mozambique.
Elda D CandaDepartment of Mental Health, Ministry of Health, Maputo, Mozambique.
Maria Eduarda FernandesDepartment of Mental Health, Ministry of Health, Maputo, Mozambique.
Teresa I Baltazar RodriguesDepartment of Mental Health, Ministry of Health, Maputo, Mozambique.
Mariel C Tai SanderDepartment of Psychiatry, New York State Psychiatric Institute and Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Claude A MellinsDepartment of Psychiatry, New York State Psychiatric Institute and Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Cristiane S DuarteDepartment of Psychiatry, New York State Psychiatric Institute and Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Palmira Fortunato Dos SantosDepartment of Mental Health, Ministry of Health, Maputo, Mozambique.
Milton L WainbergDepartment of Psychiatry, New York State Psychiatric Institute and Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.

Funding

StepWell: Stepped Care Mental Health and Substance Use Telehealth Services for COVID-19 Affected PatientsU19MH113203 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI OQUENDO, MARIA A, WAINBERG, MILTON L · 2017 to 2021
$5.7M
Global Mental Health Research Fellowship: Interventions That Make a DifferenceT32MH096724 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2012 to 2026
$4.4M
Community I-STAR Mozambique: Community Implementation of SBIRT using Technology for Alcohol use Reduction in MozambiqueR01AA025947 · NIAAA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI WAINBERG, MILTON L · 2018 to 2023
$3.4M
PALOP MENTAL HEALTH IMPLEMENTATION RESEARCH TRAININGD43TW009675 · FIC · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI Lidia Gouveia, Maria A Oquendo · 2014 to 2026
$3.2M
Youth-PRIDES: Implementing integrated, mHealth care for adolescent depressionwithin primary care clinics of MozambiqueK01MH120258 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI LOVERO, KATHRYN LYNN · 2019 to 2023
$975k
FIC NIH HHS D43 TW009675NIAAA NIH HHS R01 AA025947NIMH NIH HHS K01 MH120258NIMH NIH HHS T32 MH096724NIMH NIH HHS U19 MH113203
6 · The paper itself

Abstract

backgroundMental disorders are the leading cause of disability for youth worldwide. However, there is a dearth of validated, brief instruments to assess mental health in low- and middle-income countries (LMIC). We aimed to facilitate identification of mental disorders in LMIC contexts by adapting and validating measures of internalizing and externalizing disorders for adolescents in Mozambique, an LMIC in southeastern Africa.

methodsWe selected instruments with good support for validity in high-income and other LMIC settings: the Patient Health Questionnaire Adolescent (PHQ-A), Generalized Anxiety Disorders 7 (GAD-7), and Strengths and Difficulties Questionnaire (SDQ). Instruments were adapted by local and international mental health specialists followed by cognitive interviews (n = 48) with Mozambican adolescents. We administered the instruments along with the Miniature International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)to 485 adolescents aged 12-19 years attending two secondary schools in Maputo City, Mozambique. One week later, we re-administered instruments to a randomly selected sample of 49 adolescents.

resultsParticipants were 66.2% (n = 321) female and the average age was 15.9 (S.D = 1.7).Internal consistency (alpha = 0.80, PHQ-A; 0.84, GAD-7; 0.80, SDQ) and test-retest reliabilty (ICC = 0.74, PHQ-A; 0.70, GAD-7; 0.77, SDQ) were acceptabe for the PHQ-A, GAD-7, and the full SDQ. The SDQ internalizing subscale showed poor test-retest reliability (ICC = 0.63) and the SDQ externalizing subscale showed poor internal consistency (alpha = 0.65). All instruments demonstrated good sensitivity and specificity (> 0.70). Youden's index identified optimal cutoff scores of 8 for the PHQ-A, 5 for the GAD-7, 10 for the SDQ internalizing and 9 for the SDQ externalizing subscales, though a range of scores provided acceptable sensitivity and specificity.

conclusionsOur data supports reliability and validity of the PHQ-A, GAD-7, and SDQ instruments for rapidly assessing mental health problems in Mozambican adolescents. Use of these tools in other contexts with limited specialists may asist with expanding mental health assessment. Specific instrument and cutoff selection should be based on screening goals, treatment resources, and program objectives.

Indexed as

Mass ScreeningPatient Health QuestionnaireAdolescentChildFemaleHumansMozambiquePsychometricsReproducibility of ResultsSurveys and QuestionnairesADHDAnxietyDepressionDisruptive behavior disordersGADLMICPHQPsychometricsSDQYouth

Identifiers

PMID35962378
PMCPMC9373392

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.