Evidence map›Paper›PMID 35962334›Full record

Trial reportBMC psychiatry2022

Cost and effectiveness of one session treatment (OST) for children and young people with specific phobias compared to multi-session cognitive behavioural therapy (CBT): results from a randomised controlled trial.

Han-I Wang, Barry Wright, Lucy Tindall, Cindy Cooper, Katie Biggs, Ellen Lee, M Dawn Teare, Lina Gega, Alexander J Scott, Emily Hayward and 5 more

Open access · goldAbstract readMulticenter StudyRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in BMC psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Han-I WangDepartment of Health Sciences, Seebohm Rowntree Building, University of York, Heslington, YO10 5DD, York, UK. han-i.wang@york.ac.uk.
Barry WrightDepartment of Health Sciences, Seebohm Rowntree Building, University of York, Heslington, YO10 5DD, York, UK.
Lucy TindallLeeds and York Partnership NHS Foundation Trust, Leeds, UK.
Cindy CooperUniversity of Sheffield, Sheffield, UK.
Katie BiggsUniversity of Sheffield, Sheffield, UK.
Ellen LeeUniversity of Sheffield, Sheffield, UK.
M Dawn TeareNewcastle University, Newcastle upon Tyne, UK.
Lina GegaDepartment of Health Sciences, Seebohm Rowntree Building, University of York, Heslington, YO10 5DD, York, UK.
Alexander J ScottKeele University, Keele, UK.
Emily HaywardLeeds and York Partnership NHS Foundation Trust, Leeds, UK.
Kiera SolaimanUniversity of Sheffield, Sheffield, UK.
Thompson DavisLouisiana State University, Baton Rouge, USA.
Dean McMillanDepartment of Health Sciences, Seebohm Rowntree Building, University of York, Heslington, YO10 5DD, York, UK.
Simon GilbodyDepartment of Health Sciences, Seebohm Rowntree Building, University of York, Heslington, YO10 5DD, York, UK.
Steve ParrottDepartment of Health Sciences, Seebohm Rowntree Building, University of York, Heslington, YO10 5DD, York, UK.
University of York · GBUniversity of Sheffield · GBLeeds and York Partnership NHS Foundation Trust · GBHull York Medical School · GBKeele University · GBNewcastle University · GBUniversity of Alabama · US

Funding

Department of Health
6 · The paper itself

Abstract

backgroundIn the UK, around 93,000 (0.8%) children and young people (CYP) are experiencing specific phobias that have a substantial impact on daily life. The current gold-standard treatment-multi-session cognitive behavioural therapy (CBT) - is effective at reducing specific phobia severity; however, CBT is time consuming, requires specialist CBT therapists, and is often at great cost and limited availability. A briefer variant of CBT called one session treatment (OST) has been found to offer similar clinical effectiveness for specific phobia as multi-session CBT. The aim of this study was to assess the cost-effectiveness of OST compared to multi-session CBT for CYP with specific phobias through the Alleviating Specific Phobias Experienced by Children Trial (ASPECT), a two-arm, pragmatic, multi-centre, non-inferiority randomised controlled trial.

methodsCYP aged seven to 16 years with specific phobias were recruited nationally via Health and Social Care pathways, remotely randomised to the intervention group (OST) or the control group (CBT-based therapies) and analysed (n = 267). Resource use based on NHS and personal social services perspective and quality adjusted life years (QALYs) measured by EQ-5D-Y were collected at baseline and at six-month follow-up. Incremental cost-effectiveness ratio (ICER) was calculated, and non-parametric bootstrapping was conducted to capture the uncertainty around the ICER estimates. The results were presented on a cost-effectiveness acceptability curve (CEAC). A set of sensitivity analyses (including taking a societal perspective) were conducted to assess the robustness of the primary findings.

resultsAfter adjustment and bootstrapping, on average CYP in the OST group incurred less costs (incremental cost was -£302.96 (95% CI -£598.86 to -£28.61)) and maintained similar improvement in QALYs (QALYs gained 0.002 (95% CI - 0.004 to 0.008)). The CEAC shows that the probability of OST being cost-effective was over 95% across all the WTP thresholds. Results of a set of sensitivity analyses were consistent with the primary outcomes.

conclusionCompared to CBT, OST produced a reduction in costs and maintained similar improvement in QALYs. Results from both primary and sensitivity analyses suggested that OST was highly likely to be cost saving.

trial registrationISRCTN19883421 (30/11/2016).

Indexed as

Cognitive Behavioral TherapyPhobic DisordersAdolescentChildCost-Benefit AnalysisHumansQuality-Adjusted Life YearsQuality of LifeAdolescentChildCognitive behavioural therapyCostCost-effectivenessEQ-5D-YMental health servicesOne session treatmentPhobic disorders

Identifiers

PMID35962334
PMCPMC9372970
OpenAlexW4291158231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.