ArticleBrain structure & function2023
Homology of neocortical areas in rats and primates based on cortical type analysis: an update of the Hypothesis on the Dual Origin of the Neocortex.
Article in Brain structure & function, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 37 citations in OpenAlex.
- Regional Functional Molecular Profiles Within the Mammalian Cortex: A Commentary on Limbic Mesocortex.The Journal of comparative neurology · 2026Article
- Internal connectivity of the mouse mesocortical ring and functional implications.Brain structure & function · 2026Article
- Correspondence of large-scale functional brain network decline across aging mice and humans.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Visualizing cortical laminar architecture in the living human brain using next-generation ultra-high-gradient diffusion MRI.Communications biology · 2026Article
- Cortical Type: The Basis for a Modern Neurodevelopmental Synthesis (Ontogeny, Phylogeny, Synaptic Connectivity) of the Human Cerebral Cortex.The Journal of comparative neurology · 2026Review
- From hidden springs to endless oceans: exploring the complementary roles of the amygdala and hippocampus in phenomenal experience.Neuroscience of consciousness · 2026Article
- Cortical similarity networks in the rat brain: Postnatal development and sensitivity to early life stress.Network neuroscience (Cambridge, Mass.) · 2026Article
- Biophysical modeling of thalamocortical circuit dynamics: species-specific insights into neural synchrony, sleep spindles, and circuit mechanisms.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Complex functions of human lateral frontopolar cortex.Brain : a journal of neurology · 2025Review
- Friedrich Sanides (1914-1984).Journal of neurology · 2025Article
- The brain cortical similarity network: Development and sensitivity to early life stress in a rat model.bioRxiv : the preprint server for biology · 2025Article
- Cortical circuit principles predict patterns of trauma induced tauopathy in humans.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Distinct genetic underpinnings of inter-individual differences in the sensorimotor-association axis of cortical organisation.bioRxiv : the preprint server for biology · 2025Article
- The Cortical Structural Model Extends to Thalamocortical Connections.The European journal of neuroscience · 2025Article
- Adaptive consolidation of active inference: excitatory and inhibitory mechanisms for organizing feedforward and feedback memory systems in sleep.Cerebral cortex (New York, N.Y. : 1991) · 2025Review
- Cytoarchitectonic gradients of laminar degeneration in behavioural variant frontotemporal dementia.Brain : a journal of neurology · 2025Article
- Structural MRI of brain similarity networks.Nature reviews. Neuroscience · 2025Review
- The possibilities of conscious experience in light of the dual origin hypothesis of the neocortex.Neuroscience of consciousness · 2025Article
- Stereological Analysis of the Rhesus Monkey Perirhinal and Parahippocampal Cortices.The Journal of comparative neurology · 2024Article
- The meso-connectomes of mouse, marmoset, and macaque: network organization and the emergence of higher cognition.Cerebral cortex (New York, N.Y. : 1991) · 2024Review
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3 authors at 1 institution in 2 countries.
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Abstract
Sixty years ago, Friedrich Sanides traced the origin of the tangential expansion of the primate neocortex to two ancestral anlagen in the allocortex of reptiles and mammals, and proposed the Hypothesis on the Dual Origin of the Neocortex. According to Sanides, paraolfactory and parahippocampal gradients of laminar elaboration expanded in evolution by addition of successive concentric rings of gradually different cortical types inside the allocortical ring. Rodents had fewer rings and primates had more rings in the inner part of the cortex. In the present article, we perform cortical type analysis of the neocortex of adult rats, Rhesus macaques, and humans to propose hypotheses on homology of cortical areas applying the principles of the Hypothesis on the Dual Origin of the Neocortex. We show that areas in the outer rings of the neocortex have comparable laminar elaboration in rats and primates, while most 6-layer eulaminate areas in the innermost rings of primate neocortex lack homologous counterparts in rats. We also represent the topological distribution of cortical types in simplified flat maps of the cerebral cortex of monotremes, rats, and primates. Finally, we propose an elaboration of the Hypothesis on the Dual Origin of the Neocortex in the context of modern studies of pallial patterning that integrates the specification of pallial sectors in development of vertebrate embryos. The updated version of the hypothesis of Sanides provides explanation for the emergence of cortical hierarchies in mammals and will guide future research in the phylogenetic origin of neocortical areas.
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