Evidence map›Paper›PMID 35962148›Full record

ArticleBreast cancer research and treatment2022

A mixed-methods study of the technical feasibility and patient acceptability of a real-time adherence monitor in breast cancer survivors taking adjuvant endocrine therapy.

Emma E Bright, Sarah R Genung, Annette L Stanton, Joanna J Arch

Open access · greenAbstract read
In one paragraph

Article in Breast cancer research and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. A Systematic Review and Meta-Analysis of Interventions to Promote Adjuvant Endocrine Therapy Adherence Among Breast Cancer Survivors.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Emma E BrightDepartment of Psychology and Neuroscience, University of Colorado, Box 345, Boulder, CO, 80309-0345, USA. emma.bright@colorado.edu.ORCID http://orcid.org/0000-0001-6682-4561
Sarah R GenungDepartment of Psychology and Neuroscience, University of Colorado, Box 345, Boulder, CO, 80309-0345, USA.
Annette L StantonDepartment of Psychology, University of California, Los Angeles, CA, USA.
Joanna J ArchDepartment of Psychology and Neuroscience, University of Colorado, Box 345, Boulder, CO, 80309-0345, USA.
University of Colorado Boulder · USUniversity of California, Los Angeles · US

Funding

A Novel Values-based Intervention to Increase Endocrine Therapy Adherence among Breast Cancer SurvivorsR21CA218723 · NCI · UNIVERSITY OF COLORADO · PI ARCH, JOANNA J · 2018 to 2019
$368k
Division of Cancer Epidemiology and Genetics, National Cancer Institute R21CA218723International Breast Cancer Research Foundation BCRF-21-153NCI NIH HHS R21 CA218723
6 · The paper itself

Abstract

purposeOral anti-cancer medications are increasingly common and endocrine therapies represent the most common oral anti-cancer medications in breast cancer. Adjuvant endocrine therapies reduce the likelihood of recurrence and mortality in the approximately 80% of women diagnosed with hormone-receptor-positive breast cancer, thus rendering adherence essential. Real-time medication adherence monitors, such as the Wisepill electronic pillbox, transmit adherence data remotely, allowing for early intervention for non-adherence. However, their feasibility and acceptability have yet to be examined among breast cancer survivors taking endocrine therapies.

methodsThis study presents quantitative patient-report and technical support data and qualitative patient acceptability data on Wisepill, a common real-time adherence monitor, among 88 breast cancer survivors prescribed adjuvant endocrine therapy.

resultsThis mixed-methods study of a common real-time adherence monitor, among the first in breast cancer survivors taking adjuvant endocrine therapy, demonstrates its technical feasibility and patient acceptability.

conclusionThe use of wireless medication monitors that transmit real-time adherence data is uniquely promising for maximizing the benefits of adjuvant endocrine therapy by allowing for continuous tracking, ongoing communication with oncologic or research teams, and early intervention. This study demonstrates the feasibility and patient acceptability of one such real-time adherence monitor.

Indexed as

Breast NeoplasmsCancer SurvivorsAntineoplastic Agents, HormonalChemotherapy, AdjuvantFeasibility StudiesFemaleHumansMedication AdherenceSurvivorsAntineoplastic Agents, HormonalBreast cancerEndocrine therapyMedication adherenceReal-time adherence monitor

Identifiers

PMID35962148
PMCPMC9901531
OpenAlexW4290861077

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.