Evidence map›Paper›PMID 35962010›Full record

ArticleScientific reports2022

Association between obesity and COVID-19 mortality and length of stay in intensive care unit patients in Brazil: a retrospective cohort study.

Vitor Barreto Paravidino, Tatiana Henriques Leite, Mauro Felippe Felix Mediano, Rosely Sichieri, Gulnar Azevedo E Silva, Victor Cravo, Alex Balduino, Emmanuel Salgueiro, Bruno Adler Maccagnan Pinheiro Besen, Rodrigo de Carvalho Moreira and 4 more

Abstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Cardiovascular Statistics - Brazil 2023.Arquivos brasileiros de cardiologia · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Vitor Barreto ParavidinoDepartment of Epidemiology, Institute of Social Medicine, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil. vparavidino@gmail.com.
Tatiana Henriques LeiteDepartment of Epidemiology, Institute of Social Medicine, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Mauro Felippe Felix MedianoEvandro Chagas National Institute of Infectious Disease, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.
Rosely SichieriDepartment of Epidemiology, Institute of Social Medicine, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Gulnar Azevedo E SilvaDepartment of Epidemiology, Institute of Social Medicine, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Victor CravoHospital Vitória e Samaritano Barra, Américas Serviços Médicos, UnitedHealth Group Brazil, Rio de Janeiro, RJ, Brazil.
Alex BalduinoClinical Research, Research and Education Institute, UnitedHealth Group Brazil, Rio de Janeiro, RJ, Brazil.
Emmanuel SalgueiroHospital Vitória e Samaritano Barra, Américas Serviços Médicos, UnitedHealth Group Brazil, Rio de Janeiro, RJ, Brazil.
Bruno Adler Maccagnan Pinheiro BesenHospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Rodrigo de Carvalho MoreiraClinical Research, Research and Education Institute, UnitedHealth Group Brazil, Rio de Janeiro, RJ, Brazil.
Carlos Eduardo BrandãoDepartment of Standard Care - Amil, UnitedHealth Group, São Paulo, Brazil.
Danilo Cosme Klein GomesDepartment of Epidemiology, Institute of Social Medicine, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Cinthia Almeida Guimarães AssemanyDepartment of Epidemiology, Institute of Social Medicine, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Pedro CougoHospital Vitória e Samaritano Barra, Américas Serviços Médicos, UnitedHealth Group Brazil, Rio de Janeiro, RJ, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to evaluate the association between obesity and COVID-19 mortality and length of stay in ICU patients, and how these associations were modified by age groups. We performed a retrospective multicenter cohort study with data obtained from a hospital-based registry. The sample consisted of 8183 ICU hospitalized patients who tested positive for SARS-CoV-2. Cox proportional models were used to evaluate the association between BMI categories and COVID-19 mortality and generalized linear models for the length of stay in the ICU. After adjusting for confounders, those in the younger group with severe obesity had an increased risk of COVID-19 mortality compared to those with normal/overweight (HR 1.27; 95% CI 1.01-1.61). An increased risk of death was also observed for patients with underweight (HR 3.74; 95% CI 1.39-10.07). For patients aged ≥ 60 year, mild/moderate obesity was associated with reduced mortality risk (HR 0.87; 95% CI 0.78-0.97). For the age group < 60 year, the length of stay in ICU for those patients with severe obesity was 35% higher compared to the normal/overweight category (e

Indexed as

COVID-19Obesity, MorbidBody Mass IndexBrazilCohort StudiesHumansInfantIntensive Care UnitsLength of StayObesityOverweightRetrospective StudiesSARS-CoV-2Thinness

Identifiers

PMID35962010
PMCPMC9372981

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.