ArticleSpinal cord series and cases2022
Autonomic variability, depression and the disability paradox in spinal cord injury.
Article in Spinal cord series and cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.
- A Systematic Review of the Impact of Spinal Cord Injury on Costs and Health-Related Quality of Life.PharmacoEconomics - open · 2024Pooled it
- Delayed Withdrawal of Life-Sustaining Treatment in Disorders of Consciousness: Practical and Theoretical Considerations.Neurocritical care · 2025Review
- Challenges in Contemporary Spine Surgery: A Comprehensive Review of Surgical, Technological, and Patient-Specific Issues.Journal of clinical medicine · 2024Review
- Analysis of Influencing Factors of Major Depression After Spinal Cord Injury.Alpha psychiatry · 2024Article
- Cognitive, behavioral and psychiatric symptoms in patients with spinal cord injury: a scoping review.Frontiers in psychiatry · 2024Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designLongitudinal.
objectiveWith an increased risk of depression in spinal cord injury, the study longitudinally examines depression to understand how post-injury autonomic regulation and coping might be related to somatic and cognitive manifestations of depression after 3 years.
settingIndian Spinal Injuries Center.
methodsTwenty-eight spinal cord injury participants completed the follow-up assessment of the Patient Health Questionnaire 3 years post-injury. The participants were grouped based on post-injury autonomic regulation (high and low HRV) and the somatic and cognitive manifestation of depression reflected in a depression ratio. Wilcoxson signed-rank test tested the post-injury (T1) and 3 year follow-up (T2) depression scores.
resultsDepression score reduced after 3 years of injury (p ≤ 0.05). Only the high HRV group showed a higher depression ratio (somatic/ cognitive) atfollow-up (T2) (p ≤ 0.05). No difference was observed in post-injury coping between high and low HRV groups.
conclusionThe reduced depression score at follow-up (T2) aligns with the 'disability paradox' and mightindicate cognitive adaptation, specifically for those who showed autonomic adaptability in the form of post-injury high autonomic variability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.