Evidence map›Paper›PMID 35961303›Full record

ArticlePharmaceutical biology2022

Cytotoxic effects of extracts obtained from plants of the Oleaceae family: bio-guided isolation and molecular docking of new secoiridoids from

Khaled Ahmed Mansour, Ahmed Elbermawi, Ahmed A Al-Karmalawy, Mohamed-Farid Lahloub, Mona El-Neketi

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Plants (Basel, Switzerland) · 2023
    Article
  9. Jasminum humile (Linn) ameliorates CClInflammopharmacology · 2023
    Article
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Khaled Ahmed MansourDepartment of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.ORCID 0000-0002-0636-9533
Ahmed ElbermawiDepartment of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Ahmed A Al-KarmalawyDepartment of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University in Egypt, New Damietta, Egypt.ORCID 0000-0002-8173-6073
Mohamed-Farid LahloubDepartment of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Mona El-NeketiDepartment of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Mansoura University · EGDamietta University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextTraditionally, Oleaceae plants are used to treat many diseases, such as rheumatism, hypercholesterolaemia, or ulcers.

objectivesTo investigate the cytotoxic potential of MATERIALS AND

methodsThe 95% ethanol extracts of aerial parts of three oleaceous plants were examined for their cytotoxicity against HepG-2, MCF-7, and THP-1 cell lines using MTT assay and doxorubicin (positive control).

resultsJasmoside (

conclusionIn this study, two new compounds were purified. The biological activity highlighted jasmoside (

Indexed as

Antineoplastic AgentsJasminumOleaceaeDoxorubicinHumansIridoidsMolecular Docking SimulationPlant ExtractsAntineoplastic AgentsDoxorubicinIridoidsPlant Extractsanticancerbiological activityMTT assaySARselectivity indexStructure elucidation

Identifiers

PMID35961303
PMCPMC9377236
OpenAlexW4291033596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.