Evidence map›Paper›PMID 35961005›Full record

ArticleAnalytical chemistry2022

Effects of Molecular Size on Resolution in Charge Detection Mass Spectrometry.

Conner C Harper, Zachary M Miller, Hyuncheol Lee, Amanda J Bischoff, Matthew B Francis, David V Schaffer, Evan R Williams

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Single particle charge detection mass spectrometry enables molecular characterization of lipid nanoparticles and mRNA packaging.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Article
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  9. Review
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  11. Exosome Mediated Cell-Cell Crosstalk in Tissue Injury and Repair.Results and problems in cell differentiation · 2024
    Review
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  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Conner C HarperCollege of Chemistry, University of California, Berkeley, Berkeley, California 94720-1460, United States.
Zachary M MillerCollege of Chemistry, University of California, Berkeley, Berkeley, California 94720-1460, United States.
Hyuncheol LeeCalifornia Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, California 94720-1460, United States.
Amanda J BischoffCollege of Chemistry, University of California, Berkeley, Berkeley, California 94720-1460, United States.ORCID 0000-0003-0802-275X
Matthew B FrancisCollege of Chemistry, University of California, Berkeley, Berkeley, California 94720-1460, United States.ORCID 0000-0003-2837-2538
David V SchafferCollege of Chemistry, University of California, Berkeley, Berkeley, California 94720-1460, United States.ORCID 0000-0002-9625-0121
Evan R WilliamsCollege of Chemistry, University of California, Berkeley, Berkeley, California 94720-1460, United States.ORCID 0000-0002-1733-3018
QB3 · US

Funding

Univ of Calif Berkeley Chemistry-Biology Interface ProgramT32GM066698 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI CHANG, CHRISTOPHER J., FRANCIS, MATTHEW B · 2004 to 2023
$7.5M
Multiplexed Charge Detection Mass Spectrometer for Extended Mass and Collisional Cross Section MeasurementsR01GM139338 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Evan R Williams · 2020 to 2026
$2.9M
NIGMS NIH HHS R01 GM139338NIGMS NIH HHS T32 GM066698
6 · The paper itself

Abstract

Instrumental resolution of Fourier transform-charge detection mass spectrometry instruments with electrostatic ion trap detection of individual ions depends on the precision with which ion energy is determined. Energy can be selected using ion optic filters or from harmonic amplitude ratios (HARs) that provide Fellgett's advantage and eliminate the necessity of ion transmission loss to improve resolution. Unlike the ion energy-filtering method, the resolution of the HAR method increases with charge (improved

Indexed as

Mass SpectrometryCapsidFourier AnalysisIonsStatic ElectricityIons

Identifiers

PMID35961005
PMCPMC10389281
OpenAlexW4290931399

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.