SynthesisInvestigative ophthalmology & visual science2022
Ambient Air Pollution and Age-Related Eye Disease: A Systematic Review and Meta-Analysis.
Synthesis in Investigative ophthalmology & visual science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between ambient air pollution and age-related macular degeneration: a meta-analysis.BMC ophthalmology · 2024Pooled it
- Environmental particulate reference materials increase DCFDA fluorescence and reduce ATP-dependent viability in primary mouse retinal cells.Biochemistry and biophysics reports · 2026Article
- Plant-based diet quality and risk of age-related eye diseases: evidence from multi-cohorts with multi-omics insights.NPJ science of food · 2026Article
- Association of Air Pollution Exposure with Incident Cataract Surgery and Neovascular Age-Related Macular Degeneration in 2 French Nationwide Cohorts.Ophthalmology science · 2026Article
- Article
- Long-term exposure to fine particulate matter and its constituents is related to self-reported visual impairment among middle-aged and older adults: a longitudinal study in China.BMC public health · 2025Article
- Prevalence and Risk Factors of Open-Angle Glaucoma in an Adult Chinese American Population: The Chinese American Eye Study.American journal of ophthalmology · 2025Article
- Prevalence and associated factors of vitreoretinal interface disorders using multicolour OCT among Chinese population in Fujian eye study.Scientific reports · 2025Article
- Ambient air pollution exposure and incidence of cataract surgery: The prospective 3City-Alienor study.Acta ophthalmologica · 2025Article
- PMScientific reports · 2025Article
- Association of Per- and Polyfluoroalkyl Substance Exposure With Cataract Prevalence Among U.S. Adults: A NHANES Analysis (2005-2008).Translational vision science & technology · 2025Article
- Residential greenness, air pollution and visual impairment: a prospective cohort study.BMC public health · 2024Article
- Association of Ambient Air Pollution Exposure With Incident Glaucoma: 12-Year Evidence From the UK Biobank Cohort.Investigative ophthalmology & visual science · 2024Article
- Review
- Changing Trends in the Global Burden of Cataract Over the Past 30 Years: Retrospective Data Analysis of the Global Burden of Disease Study 2019.JMIR public health and surveillance · 2023Article
- Towards modifying the genetic predisposition for glaucoma: An overview of the contribution and interaction of genetic and environmental factors.Molecular aspects of medicine · 2023Review
- A Review of Ambient Air Pollution as a Risk Factor for Posterior Segment Ocular Diseases.Journal of clinical medicine · 2023Review
- Time trends and gender disparities of Chinese cataract burden and their predictions.International journal of ophthalmology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To compare the burden of age-related eye diseases among adults exposed to higher versus lower levels of ambient air pollutants. Methods: MEDLINE, EMBASE, and Scopus were searched for relevant articles until September 30, 2021. Inclusion criteria included studies of adults, aged 40+ years, that provided measures of association between the air pollutants (nitrogen dioxide, carbon monoxide [CO], sulfur dioxide, ozone [O3], particulate matter [PM] less than 2.5 µm in diameter [PM2.5], and PM less than 10 µm in diameter [PM10]) and the age-related eye disease outcomes of glaucoma, age-related macular degeneration (AMD), or cataract. Pooled odds ratio (OR) estimates and 95% confidence intervals (CIs) were calculated using a random-effects meta-analysis model. PROSPERO registration ID: CRD42021250078. Results: A total of eight studies were included in the review. Consistent evidence for an association was found between PM2.5 and glaucoma, with four of four studies reporting a positive association. The pooled OR for each 10-µg/m3 increase of PM2.5 on glaucoma was 1.18 (95% CI, 0.95-1.47). Consistent evidence was also found for O3 and cataract, with three of three studies reporting an inverse association. Two of two studies reported a null association between PM2.5 and cataract, while one of one studies reported a positive association between PM10 and cataract. One of one studies reported a positive relationship between CO and AMD. Other relationships were less consistent between studies. Conclusions: Current evidence suggests there may be an association between some air pollutants and cataract, AMD, and glaucoma.
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