Evidence map›Paper›PMID 35960427›Full record

ReviewOrigins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life2022

Asymmetric Autocatalysis as an Efficient Link Between the Origin of Homochirality and Highly Enantioenriched Compounds.

Kenso Soai, Tsuneomi Kawasaki, Arimasa Matsumoto

Abstract readReview
PubMed Publisher
In one paragraph

Review in Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kenso SoaiDepartment of Applied Chemistry, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo, 162-8601, Japan. soai@rs.kagu.tus.ac.jp.ORCID http://orcid.org/0000-0002-8060-444X
Tsuneomi KawasakiDepartment of Applied Chemistry, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo, 162-8601, Japan.
Arimasa MatsumotoDepartment of Chemistry, Nara Women's University, Kita-Uoya Nishi-machi, Nara, 630-8506, Japan.

Funding

Japan Society for the Promotion of Science 15H03781Japan Society for the Promotion of Science 17H05384Japan Society for the Promotion of Science 18H04518Japan Society for the Promotion of Science 19K05482Japan Society for the Promotion of Science 19K22190Japan Society for the Promotion of Science 20H04674Japan Society for the Promotion of Science 23685012Japan Society for the Promotion of Science 26810026
6 · The paper itself

Abstract

Biological homochirality of essential components such as L-amino acids and D-sugars is prerequisite for the emergence, evolution and the maintenance of life. Implication of biological homochirality is described. Considerable interest has been focused on the origin and the process leading to the homochirality. Asymmetric autocatalysis with amplification of enantiomeric excess (ee), i.e., the Soai reaction, is capable to link the low ee induced by the proposed origins of chirality such as circularly polarized light and high ee of the organic compound. Absolute asymmetric synthesis without the intervention of any chiral factor was achieved in the Soai reaction.

Indexed as

Amino AcidsSugarsCatalysisStereoisomerismAmino AcidsSugarsAmplification of enantiomeric excessAsymmetric autocatalysisOrigin of homochiralitySelf-replicationSoai reactionSymmetry breaking

Identifiers

PMID35960427

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.