Evidence map›Paper›PMID 35960317›Full record

ArticleAnalytical and bioanalytical chemistry2022

Critical evaluation of the role of external calibration strategies for IM-MS.

Max L Feuerstein, Maykel Hernández-Mesa, Younes Valadbeigi, Bruno Le Bizec, Stephan Hann, Gaud Dervilly, Tim Causon

Abstract read
In one paragraph

Article in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
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  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Max L FeuersteinDepartment of Chemistry, Institute of Analytical Chemistry, University of Natural Resources and Life Sciences, Muthgasse 18, 1190, Vienna, Austria.
Maykel Hernández-MesaOniris, INRAE, LABERCA, 44300, Nantes, France.
Younes ValadbeigiDepartment of Chemistry, Institute of Analytical Chemistry, University of Natural Resources and Life Sciences, Muthgasse 18, 1190, Vienna, Austria.
Bruno Le BizecOniris, INRAE, LABERCA, 44300, Nantes, France.
Stephan HannDepartment of Chemistry, Institute of Analytical Chemistry, University of Natural Resources and Life Sciences, Muthgasse 18, 1190, Vienna, Austria.
Gaud DervillyOniris, INRAE, LABERCA, 44300, Nantes, France.
Tim CausonDepartment of Chemistry, Institute of Analytical Chemistry, University of Natural Resources and Life Sciences, Muthgasse 18, 1190, Vienna, Austria. Tim.Causon@boku.ac.at.

Funding

Austrian Science Fund M 2938Campus France 44087WBOeAD-GmbH FR 11/2020
6 · The paper itself

Abstract

The major benefits of integrating ion mobility (IM) into LC-MS methods for small molecules are the additional separation dimension and especially the use of IM-derived collision cross sections (CCS) as an additional ion-specific identification parameter. Several large CCS databases are now available, but outliers in experimental interplatform IM-MS comparisons are identified as a critical issue for routine use of CCS databases for identity confirmation. We postulate that different routine external calibration strategies applied for traveling wave (TWIM-MS) in comparison to drift tube (DTIM-MS) and trapped ion mobility (TIM-MS) instruments is a critical factor affecting interplatform comparability. In this study, different external calibration approaches for IM-MS were experimentally evaluated for 87 steroids, for which

Indexed as

CalibrationChromatography, LiquidMass SpectrometryReference StandardsCCSDFTIon mobility-mass spectrometryStable isotope labellingSteroids

Identifiers

PMID35960317
PMCPMC9482903

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.