Evidence map›Paper›PMID 35959757›Full record

ArticleIndian pediatrics2022

Preterm General Movements in Prediction of Neurodevelopmental Disability and Cerebral Palsy at Two Years: A Prospective Cohort Study.

Hima B John, Samuel P Oommen, T O Swathi, Manish Kumar, Ragnhild Stoen, Lars Adde

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Article in Indian pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Hima B JohnDepartment of Neonatology, Christian Medical College, Vellore, Tamil Nadu, India.
Samuel P OommenDevelopmental Pediatrics Unit, Christian Medical College, Vellore, Tamil Nadu, India. Correspondence to: Dr Samuel P Oommen, Professor, Developmental Pediatrics Unit, Department of Pediatrics, Christian Medical College, Vellore 632 004, Tamil Nadu. devpaed@cmcvellore.ac.in.
T O SwathiDevelopmental Pediatrics Unit, Christian Medical College, Vellore, Tamil Nadu, India.
Manish KumarDepartment of Neonatology, Christian Medical College, Vellore, Tamil Nadu, India.
Ragnhild StoenSt. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Lars AddeDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
Christian Medical College & Hospital · INChristian Medical College · INNorwegian University of Science and Technology · NOSt Olav's University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: A neurological assessment before discharge from the NICU would enable early targeted intervention to mitigate the risk and severity of cerebral palsy (CP) and neurodevelop-mental disability.

objectiveTo assess the accuracy of general movements (GM) in the preterm and fidgety movement periods in predicting neurodevelopmental disability and cerebral palsy in very preterm infants (≤32 weeks gestational age) at 18-24 months corrected gestational age. STUDY

designProspective cohort study.

participantsOne hundred and seventy very preterm infants, mean (SD) gestation 29.8 (1.32) weeks, and birthweight 1215 (226) g. OUTCOMES: Infants underwent GM assessments in the preterm period (31-36 weeks post-conception age) and fidgety movement period (8-18 weeks post term age). Neurodevelop-mental outcomes were assessed in 127 children using the Griffiths Mental Developmental Scales-2.

resultsNine children had neurodevelopmental disability (two infants with cerebral palsy and seven with global developmental delay. The relative risk (95% CI) for neurodevelopmental disability was 1.46 (0.31-6.89) with preterm movements and 6.07 (0.97 - 38.05) with fidgety movements. Sensitivity and specificity values for the prediction of neurodevelopmental disability were 33% and 64% in the preterm period and 25% and 92% in the fidgety movement period, respectively. The sensitivity and specificity values for prediction of CP were 50% and 63% in the preterm period and 100% and 93% in the fidgety movement period, respectively.

conclusionPreterm movements showed lower sensitivity and specificity than fidgety movements in predicting later CP and neurodevelopmental disability in preterm infants.

Indexed as

Cerebral PalsyChildChild, PreschoolGestational AgeHumansInfantInfant, NewbornInfant, PrematureMovementProspective Studies

Identifiers

PMID35959757
OpenAlexW4302342244

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.