Evidence map›Paper›PMID 35959639›Full record

Observational studyEuropean journal of cancer care2022

Co-designing a behavioural intervention for reducing the impact of chemotherapy-induced peripheral neuropathy symptoms: An evidence- and theory-driven approach.

Mary Anne Lagmay Tanay, Jo Armes, Catherine Oakley, Liz Bryson, Robin Johnston, Rona Moss-Morris, Anne Marie Rafferty, Jose Roca, Lesley Sage, Deb Tanner and 3 more

Abstract readObservational Study
In one paragraph

Observational study in European journal of cancer care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Developing an Intervention for Safe Hospital Insulin Use for Older Adults With Diabetes Undergoing Surgical Admission (SHINE Study): A Co-Design Study.Health expectations : an international journal of public participation in health care and health policy · 2026
    Article
  3. Article
  4. 'Why, Can I Not Have Control of My Own Insulin?': Qualitative Exploration Amongst Older Adults With Diabetes With Lived Experience of Surgical Hospital Admission.Health expectations : an international journal of public participation in health care and health policy · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Striding beyond numbness: a non-randomized controlled study of an exercise program for breast cancer patients with chemotherapy-induced peripheral neuropathy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  9. Reflections on the opportunities and challenges of applying experience-based co-design (EBCD) to phase 1 clinical trials in oncology.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
  10. Observational
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mary Anne Lagmay TanayFlorence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King's College London, London, UK.ORCID https://orcid.org/0000-0002-3637-6742
Jo ArmesSchool of Health Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
Catherine OakleyGuy's Cancer, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
Liz BrysonPatient Expert.
Robin JohnstonPatient Expert.
Rona Moss-MorrisInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Anne Marie RaffertyFlorence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King's College London, London, UK.
Jose RocaGuy's Cancer, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
Lesley SagePatient Expert.
Deb TannerPatient Expert.
Lauren UrwinOncology and Haematology Rehabilitation Unit, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
Toni WyattOncology and Haematology Rehabilitation Unit, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
Glenn RobertFlorence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King's College London, London, UK.

Funding

National Institute for Health Research DRF-2018-11-ST2-017
6 · The paper itself

Abstract

objectiveThis study aims to co-design an evidence- and theory-based behavioural intervention to reduce the impact of chemotherapy-induced peripheral neuropathy (CIPN) symptoms on patients' quality of life.

methodsGuided by the Medical Research Council Framework for developing and evaluating complex interventions, our intervention development process was guided by (a) findings of systematic reviews, (b) inductive analysis of 39 h of observational fieldwork, 12 patient and 11 clinician interviews, (c) deductive analysis using the Common-Sense Model to develop a Self-Regulation Model of CIPN and (d) 17 patients and 18 clinicians co-designing the intervention.

resultsCIPN perception and coping behaviours were highlighted as processes to target when co-designing an intervention. The processes targeted in our intervention are CIPN perception and coping behaviours, namely, (a) self-monitoring of symptoms, (b) communicating and early reporting of symptoms to clinicians, (c) participating in making chemotherapy dose reduction decisions with their clinicians and (d) engaging in self-management and safety strategies to reduce impact of CIPN symptoms. To address these, a behavioural intervention was deemed suitable.

conclusionWe developed a self-regulation model of CIPN and a logic model for documenting the proposed mechanism of action of our co-designed behavioural intervention for reducing impact of CIPN symptoms.

Indexed as

Antineoplastic AgentsPeripheral Nervous System DiseasesHumansQuality of LifeSystematic Reviews as TopicAntineoplastic Agentscancerchemotherapychemotherapy-induced peripheral neuropathyCommon Sense Modelexperience-based co-designintervention development

Identifiers

PMID35959639
PMCPMC9786800

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.