Evidence map›Paper›PMID 35959504›Full record

ArticleTherapeutic advances in chronic disease2022

Incidence, causes, and predictors of unsuccessful decannulation following prolonged weaning.

Alessandro Ghiani, Konstantinos Tsitouras, Joanna Paderewska, Katrin Milger, Swenja Walcher, Mareike Weiffenbach, Claus Neurohr, Nikolaus Kneidinger

Abstract read
In one paragraph

Article in Therapeutic advances in chronic disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Tracheostomy Decannulation Practices in Indian Intensive Care Units: A National Cross-sectional Survey of Intensive Care Unit Consultants.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alessandro GhianiLung Center Stuttgart - Schillerhoehe Lung Clinic, Department of Pulmonology and Respiratory Medicine, Affiliated to the Robert-Bosch-Hospital GmbH, Auerbachstr. 110, 70376 Stuttgart, Germany.ORCID https://orcid.org/0000-0002-4137-5373
Konstantinos TsitourasLung Center Stuttgart - Schillerhoehe Lung Clinic, Department of Pulmonology and Respiratory Medicine, Affiliated to the Robert-Bosch-Hospital GmbH, Stuttgart, Germany.
Joanna PaderewskaLung Center Stuttgart - Schillerhoehe Lung Clinic, Department of Pulmonology and Respiratory Medicine, Affiliated to the Robert-Bosch-Hospital GmbH, Stuttgart, Germany.
Katrin MilgerDepartment of Internal Medicine V (Pulmonology), Ludwig-Maximilians-University (LMU) of Munich, Munich, Germany.
Swenja WalcherLung Center Stuttgart - Schillerhoehe Lung Clinic, Department of Pulmonology and Respiratory Medicine, Affiliated to the Robert-Bosch-Hospital GmbH, Stuttgart, Germany.
Mareike WeiffenbachDepartment of Acute Geriatrics and Geriatric Rehabilitation, Robert-Bosch-Hospital GmbH, Stuttgart, Germany.
Claus NeurohrLung Center Stuttgart - Schillerhoehe Lung Clinic, Department of Pulmonology and Respiratory Medicine, Affiliated to the Robert-Bosch-Hospital GmbH, Stuttgart, Germany.
Nikolaus KneidingerDepartment of Internal Medicine V (Pulmonology), Ludwig-Maximilians-University (LMU) of Munich, Munich, Germany.ORCID https://orcid.org/0000-0001-7583-0453

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Liberation from prolonged tracheostomy ventilation involves ventilator weaning and removal of the tracheal cannula (referred to as decannulation). This study evaluated the incidence, causes, and predictors of unsuccessful decannulation following prolonged weaning. Methods: Observational retrospective cohort study of 532 prolonged mechanically ventilated, tracheotomized patients treated at a specialized weaning center between June 2013 and January 2021. We summarized the causes for unsuccessful decannulations and used a binary logistic regression analysis to derive and validate associated predictors. Results: Failure to decannulate occurred in 216 patients (41%). The main causes were severe intensive care unit (ICU)-acquired dysphagia (64%), long-term ventilator dependence following weaning failure (41%), excessive respiratory secretions (12%), unconsciousness (4%), and airway obstruction (3%). Predictors of unsuccessful decannulation from any cause were age [odds ratio (OR) = 1.04 year Conclusion: Failure to decannulate after prolonged weaning occurred in 41%, mainly resulting from persistent ICU-acquired dysphagia and long-term ventilator dependence following weaning failure, each associated with its own set of predictors.

Indexed as

dysphagiamechanical ventilationnon-invasive ventilationtracheostomyventilator weaning

Identifiers

PMID35959504
PMCPMC9358569

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.