Evidence map›Paper›PMID 35959428›Full record

ArticleFrontiers in pharmacology2022

The effects of mango leaf extract during adolescence and adulthood in a rat model of schizophrenia.

Jose Antonio Garcia-Partida, Sonia Torres-Sanchez, Karina MacDowell, Maria Teresa Fernández-Ponce, Lourdes Casas, Casimiro Mantell, María Luisa Soto-Montenegro, Diego Romero-Miguel, Nicolás Lamanna-Rama, Juan Carlos Leza and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Jose Antonio Garcia-PartidaNeuropsychopharmacology and Psychobiology Research Group, Department of Neuroscience, University of Cádiz, Cádiz, Spain.
Sonia Torres-SanchezInstituto de Investigación e Innovación en Ciencias Biomédicas de Cádiz, INiBICA, Hospital Universitario Puerta del Mar, Cádiz, Spain.
Karina MacDowellCiber of Mental Health (CIBERSAM), ISCIII, Madrid, Spain.
Maria Teresa Fernández-PonceDepartment of Chemical Engineering and Food Technology, Science Faculty, University of Cádiz, Cádiz, Spain.
Lourdes CasasDepartment of Chemical Engineering and Food Technology, Science Faculty, University of Cádiz, Cádiz, Spain.
Casimiro MantellDepartment of Chemical Engineering and Food Technology, Science Faculty, University of Cádiz, Cádiz, Spain.
María Luisa Soto-MontenegroCiber of Mental Health (CIBERSAM), ISCIII, Madrid, Spain.
Diego Romero-MiguelInstituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Nicolás Lamanna-RamaInstituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Juan Carlos LezaCiber of Mental Health (CIBERSAM), ISCIII, Madrid, Spain.
Manuel DescoCiber of Mental Health (CIBERSAM), ISCIII, Madrid, Spain.
Esther BerrocosoInstituto de Investigación e Innovación en Ciencias Biomédicas de Cádiz, INiBICA, Hospital Universitario Puerta del Mar, Cádiz, Spain.
Universidad de Cádiz · ESUniversidad Carlos III de Madrid · ESUniversidad Complutense de Madrid · ESHospital General Universitario Gregorio Marañón · ESHospital Universitario Puerta del Mar · ESInstituto de Salud Carlos III · ESUniversidad Rey Juan Carlos · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is evidence that in schizophrenia, imbalances in inflammatory and oxidative processes occur during pregnancy and in the early postnatal period, generating interest in the potential therapeutic efficacy of anti-inflammatory and antioxidant compounds. Mangiferin is a polyphenolic compound abundant in the leaves of

Indexed as

magnetic resonace imaging (MRI)mangiferinneuroinflammationoxidative/nitrosative stressPoly I:Cschizophrenia

Identifiers

PMID35959428
PMCPMC9360613
OpenAlexW4287921922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.