Evidence map›Paper›PMID 35959366›Full record

ReviewFrontiers in cellular and infection microbiology2022

Microenvironmental Factors that Shape Bacterial Metabolites in Inflammatory Bowel Disease.

Lacey R Lopez, Ju-Hyun Ahn, Tomaz Alves, Janelle C Arthur

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Deciphering the Implications ofPathogens (Basel, Switzerland) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lacey R LopezDepartment of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Ju-Hyun AhnDepartment of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Tomaz AlvesDivision of Comprehensive Oral Health, Adams School of Dentistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Janelle C ArthurDepartment of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
University of North Carolina at Chapel Hill · US

Funding

National Gnotobiotic Rodent Resource CenterP40OD010995 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ryan B Sartor · 2012 to 2026
$9.7M
Microbiota-mediated fibrotic remodeling in the inflamed intestineR01DK124617 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ARTHUR, JANELLE C · 2020 to 2024
$1.9M
Novel high-throughput in vivo approach to define pathobionts driving colitisR21AI159786 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ARTHUR, JANELLE C · 2021 to 2022
$428k
NIAID NIH HHS R21 AI159786NIDDK NIH HHS R01 DK124617NIH HHS P40 OD010995
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a significant global health problem that involves chronic intestinal inflammation and can involve severe comorbidities, including intestinal fibrosis and inflammation-associated colorectal cancer (CRC). Disease-associated alterations to the intestinal microbiota often include fecal enrichment of

Indexed as

Gastrointestinal MicrobiomeInflammatory Bowel DiseasesBacteriaDysbiosisEnterobacteriaceaeFibrosisHumansInflammationcolorectal cancerEscherichia coliinflammationinflammatory bowel diseasemetabolitesmetalmicrobiotatherapeutics

Identifiers

PMID35959366
PMCPMC9362432
OpenAlexW4285588918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.