ArticleEmergency medicine international2022
The Association between Systemic Immune-Inflammation Index and All-Cause Mortality in Acute Ischemic Stroke Patients: Analysis from the MIMIC-IV Database.
Article in Emergency medicine international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prognostic assessment of acute ischemic stroke by systemic immune-inflammatory index: a comprehensive meta-analysis of multidimensional outcomes.Frontiers in neurology · 2025Pooled it
- Association of the systemic immune-inflammation index (SII) and clinical outcomes in patients with stroke: A systematic review and meta-analysis.Frontiers in immunology · 2022Pooled it
- Association between early intravenous magnesium sulfate administration and mortality according to systemic immune-inflammation index in critically ill patients with acute heart failure: A retrospective cohort study.American heart journal plus : cardiology research and practice · 2026Article
- Baseline and 72-h dynamic laboratory deficit burden for mortality through day 90 after acute ischemic stroke in critical care: landmark analyses with temporal validation.Frontiers in neurology · 2026Article
- Systemic immune-inflammation index, stress hyperglycemia ratio and triglyceride-glucose index in acute ischemic stroke: an integrated inflammation-stress-metabolism perspective.Frontiers in neurology · 2026Review
- Relationship Between the Systemic Immune-Inflammation Index and Non-Dipper Blood Pressure Status in Normotensive Patients With Prediabetes.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Predictive value of traditional laboratory parameters and inflammatory indices for same-day seizure recurrence in patients with epileptic seizures.Epilepsia open · 2025Article
- Article
- Inflammatory Burden Index and One-Year Clinical Outcomes in Large Artery Atherosclerosis Ischemic Stroke: A Multicenter Prospective Study.European journal of neurology · 2025Article
- Associations of the C-reactive protein-albumin-lymphocyte index with all-cause and cardiovascular mortality among individuals with cardiovascular disease: evidence from the NHANES 2001-2010.BMC cardiovascular disorders · 2025Article
- Association of systemic immune-inflammation index with severity in acute ischemic stroke patients: a cross-sectional study.Frontiers in neurology · 2025Article
- The association between the systemic immune-inflammation index and in-hospital mortality among acute ischemic stroke with atrial fibrillation patients undergoing intravenous thrombolysis.Frontiers in cardiovascular medicine · 2025Article
- The systemic immune-inflammation index and systemic inflammation response index are useful for predicting mortality in patients with diabetic nephropathy.Diabetology & metabolic syndrome · 2024Article
- Red blood cell-derived materials for cancer therapy: Construction, distribution, and applications.Materials today. Bio · 2024Review
- Association between systemic immune inflammation Index and all-cause mortality in incident peritoneal dialysis-treated CKD patients: a multi-center retrospective cohort study.BMC nephrology · 2024Article
- Elevated postoperative systemic immune-inflammation index associates with acute kidney injury after cardiac surgery: a large-scale cohort study.Frontiers in cardiovascular medicine · 2024Article
- Relationship Between Systemic Immune-Inflammation Index and Risk of Respiratory Failure and Death in COPD: A Retrospective Cohort Study Based on the MIMIC-IV Database.International journal of chronic obstructive pulmonary disease · 2024Article
- Body fluids biomarkers associated with prognosis of acute ischemic stroke: progress and prospects.Future science OA · 2024Review
- Association between admission systemic immune-inflammation index and mortality in critically ill patients with sepsis: a retrospective cohort study based on MIMIC-IV database.Clinical and experimental medicine · 2023Article
- Association of inflammatory markers with all-cause mortality and cardiovascular mortality in postmenopausal women with osteoporosis or osteopenia.BMC women's health · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Acute ischemic stroke (AIS) is a devastating disease and remains the leading cause of death and disability. This retrospective study aims to investigate associations between systemic immune-inflammation index (SII) and all-cause mortality in patients with AIS. Results: After adjusting for potential covariates, the highest quartiles of SII versus the lowest quartiles of SII, the HR was 2.74 (CI 1.79-4.19, Conclusion: Elevated SII of patients with acute ischemic stroke increased the risk of 30-day all-cause mortality. SII may serve as a useful marker to elucidate the role of thrombocytosis, inflammation, and immunity interaction in the development of AIS.
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Registered trials
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