ReviewCureus2022
Stress-Induced Hyperglycemia: Consequences and Management.
Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
100 citing papers in PubMed, 7 syntheses or guidelines pooled it, 133 citations in OpenAlex.
- Association between stress hyperglycemia ratio and prognosis of patients hospitalized with COVID-19: A meta-analysis.Journal of diabetes investigation · 2026Pooled it
- Association between stress hyperglycemia and pneumonia in patients with stroke: a systematic review and meta-analysis.BMC pulmonary medicine · 2025Pooled it
- Effectiveness of Acupressure on Sleep Quality Among Inpatients: A Systematic Review and Meta-Analysis.Nursing & health sciences · 2025Pooled it
- Stress-induced hyperglycemia and mortality in patients with traumatic brain injury without preexisting diabetes: A meta-analysis.Biomolecules & biomedicine · 2025Pooled it
- Stress-induced hyperglycemia and mortality of non-diabetic patients with sepsis: a meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Fasting blood glucose-to-glycated hemoglobin ratio and functional outcomes in patients with ischemic stroke following endovascular treatment-a meta-analysis.Frontiers in neurology · 2025Pooled it
- Association between glucose levels at admission and outcomes of pneumonia: a systematic review and meta-analysis.BMC pulmonary medicine · 2024Pooled it
- Impact of telemonitoring on glycemic control and quality of life in pediatric patients with type 1 diabetes, single center interventional control study.BMC pediatrics · 2026Trial
- Article
- Impact of Short-term Rehabilitation on Chronic Stress-induced Brain Alterations and Associated Cognitive Deficits.Annals of neurosciences · 2026Article
- Association between stress hyperglycemia ratio and 72-hour delirium in critically ill patients: A retrospective cohort study from the MIMIC-IV database.Metabolism open · 2026Article
- SARS-CoV-2 and diabetes: a post-pandemic reappraisal.Diabetologia · 2026Review
- Glycemic Status and Glycemic Variability Related to Mortality and Morbidity in Critically III Diabetic and Non-Diabetic Patients: A Prospective Observational Study.Clinics and practice · 2026Article
- Biomarker-Based Prediction of Treatment Outcomes in Pediatric Intussusception: A Retrospective Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
- Incidence of diabetes mellitus following hospitalisation with influenza: a population-based cohort study in England.BMJ open · 2026Article
- Article
- Time-dependent plasma metabolic shifts and mechanistic insights into systemic consequences of cerebral ischemia in middle-aged patients.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- Development and validation of glucose trajectory subphenotypes in critically ill patients on early enteral nutrition: a retrospective cohort study.Scientific reports · 2026Article
- Prognostic Value of Stress-Induced Hyperglycemia in High-Acuity Emergency Department Patients.Journal of clinical medicine · 2026Article
- Association between stress hyperglycemia ratio and ICU delirium among critically ill adults in MIMIC-IV.Scientific reports · 2026Article
40 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyperglycemia during stress is a common occurrence seen in patients admitted to the hospital. It is defined as a blood glucose level above 180mg/dl in patients without pre-existing diabetes. Stress-induced hyperglycemia (SIH) occurs due to an illness that leads to insulin resistance and decreased insulin secretion. Such a mechanism causes elevated blood glucose and produces a complex state to manage with external insulin. This article compiles various studies to explain the development and consequences of SIH in the critically ill that ultimately lead to an increase in mortality while also discussing the dire impact of SIH on certain acute illnesses like myocardial infarction and ischemic stroke. It also evaluates multiple studies to understand the management of SIH with insulin and proper nutritional therapy in the hospitalized patients admitted to the Intensive care unit (ICU) alongside the non-critical care unit. While emphasizing the diverse effects of improper control of SIH in the hospital, this article elucidates and discusses the importance of formulating a discharge plan due to an increased risk of type 2 diabetes in the recovered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.