Evidence map›Paper›PMID 35958984›Full record

ReviewFrontiers in neuroscience2022

The neurobiology of misophonia and implications for novel, neuroscience-driven interventions.

Andrada D Neacsiu, Victoria Szymkiewicz, Jeffrey T Galla, Brenden Li, Yashaswini Kulkarni, Cade W Spector

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06333925 (Using Neurostimulation to Accelerate Change in Misophonia), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06333925 nacompletednot on this mapstarted 2024, after this paper: background citation

Using Neurostimulation to Accelerate Change in Misophonia: a Pilot Study

TypeinterventionalSponsorDuke UniversityRan2024 to 2026Enrolled59ConditionsMisophonia, Emotion Dysregulation, Sensory Processing Disorder, Auditory Over ResponsivityArmsHigh Frequency Repetitive Transcranial Magnetic Stimulation (HF rTMS), Sham Repetitive Transcranial Magnetic Stimulation (sham- rTMS), Cognitive Restructuring
3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
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  11. Review
  12. Article
  13. How auditory processing influences the autistic profile: A review.Autism research : official journal of the International Society for Autism Research · 2024
    Review
  14. Article
  15. Article
  16. Did Kant suffer from misophonia?Frontiers in psychology · 2024
    Article
  17. Article
  18. Mindfulness and cognitive emotion regulation in pediatric misophonia.Journal of contextual behavioral science · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrada D NeacsiuDuke Center for Misophonia and Emotion Regulation, Duke Brain Stimulation Research Center, Department of Psychiatry and Behavioral Neuroscience, School of Medicine, Duke University, Durham, NC, United States.
Victoria SzymkiewiczDepartment of Psychology and Neuroscience, Duke University, Durham, NC, United States.
Jeffrey T GallaDepartment of Psychology and Neuroscience, Duke University, Durham, NC, United States.
Brenden LiDepartment of Psychology and Neuroscience, Duke University, Durham, NC, United States.
Yashaswini KulkarniDepartment of Psychology and Neuroscience, Duke University, Durham, NC, United States.
Cade W SpectorDepartment of Philosophy, Duke University, Durham, NC, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decreased tolerance in response to specific every-day sounds (misophonia) is a serious, debilitating disorder that is gaining rapid recognition within the mental health community. Emerging research findings suggest that misophonia may have a unique neural signature. Specifically, when examining responses to misophonic trigger sounds, differences emerge at a physiological and neural level from potentially overlapping psychopathologies. While these findings are preliminary and in need of replication, they support the hypothesis that misophonia is a unique disorder. In this theoretical paper, we begin by reviewing the candidate networks that may be at play in this complex disorder (e.g., regulatory, sensory, and auditory). We then summarize current neuroimaging findings in misophonia and present areas of overlap and divergence from other mental health disorders that are hypothesized to co-occur with misophonia (e.g., obsessive compulsive disorder). Future studies needed to further our understanding of the neuroscience of misophonia will also be discussed. Next, we introduce the potential of neurostimulation as a tool to treat neural dysfunction in misophonia. We describe how neurostimulation research has led to novel interventions in psychiatric disorders, targeting regions that may also be relevant to misophonia. The paper is concluded by presenting several options for how neurostimulation interventions for misophonia could be crafted.

Indexed as

interventionmisophonianeuroscienceneurostimulationreview

Identifiers

PMID35958984
PMCPMC9359080

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.