Evidence map›Paper›PMID 35958878›Full record

ArticleJournal of immunology research2022

Expanded CD1c

Guowei Qiu, Sheng Zhong, Jun Xie, Hui Feng, Songtao Sun, Chenxin Gao, Xirui Xu, Bingxin Kang, Hui Xu, Chi Zhao and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Expanded CD1cJournal of immunology research · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Guowei QiuShanghai University of Traditional Chinese Medicine, Shanghai, China.
Sheng ZhongDepartment of Orthopedics, Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jun XieDepartment of Orthopedics, Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Hui FengDepartment of Orthopedics, Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Songtao SunDepartment of Orthopedics, Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Chenxin GaoDepartment of Orthopedics, Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xirui XuDepartment of Orthopedics, Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Bingxin KangDepartment of Rehabilitation, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Hui XuHenan University of Traditional Chinese Medicine, Zhengzhou, China.
Chi ZhaoShanghai University of Traditional Chinese Medicine, Shanghai, China.
Lei RanShanghai University of Traditional Chinese Medicine, Shanghai, China.
A XinyuShanghai University of Traditional Chinese Medicine, Shanghai, China.
Bo XuShanghai University of Traditional Chinese Medicine, Shanghai, China.
Xiaohui MengShanghai University of Traditional Chinese Medicine, Shanghai, China.
Lu MengThe Center for Microbes, Development and Health, Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences/University of Chinese Academy of Sciences, Shanghai, China.ORCID https://orcid.org/0000-0001-7050-4296
Xiaoming ZhangThe Center for Microbes, Development and Health, Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences/University of Chinese Academy of Sciences, Shanghai, China.ORCID https://orcid.org/0000-0001-6732-9132
Lianbo XiaoShanghai University of Traditional Chinese Medicine, Shanghai, China.ORCID https://orcid.org/0000-0001-9305-0776
Shanghai University of Traditional Chinese Medicine · CNInstitut Pasteur of Shanghai · CNFirst Affiliated Hospital of Henan University · CNHenan University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanisms underlying osteoarthritis (OA) have recently been hypothesized to involve a dysfunctional immune system. In this study, we collected synovium, synovial fluid (SF), and peripheral blood from 21 patients. Mononuclear cells were characterized using FCM. H&E staining and mIHC histological assessment of synovium were performed. Cytokine levels in the SF were measured using ELISA. We observed similar frequencies of immune cells in the synovium and SF, which were enriched in DCs. Notably, CD1c

Indexed as

CD8-Positive T-LymphocytesOsteoarthritisAntigens, CDAntigens, CD1Antigens, Differentiation, MyelomonocyticCD163 AntigenDisease ProgressionGlycoproteinsHumansReceptors, Cell SurfaceSynovial FluidSynovial MembraneAntigens, CDAntigens, CD1Antigens, Differentiation, MyelomonocyticCD163 AntigenCD1C protein, humanGlycoproteinsReceptors, Cell Surface

Identifiers

PMID35958878
PMCPMC9359855
OpenAlexW4289344578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.