Evidence map›Paper›PMID 35958638›Full record

SynthesisFrontiers in psychiatry2022

Digital phenotype of mood disorders: A conceptual and critical review.

Redwan Maatoug, Antoine Oudin, Vladimir Adrien, Bertrand Saudreau, Olivier Bonnot, Bruno Millet, Florian Ferreri, Stephane Mouchabac, Alexis Bourla

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. Digital Neuropsychology beyond Computerized Cognitive Assessment: Applications of Novel Digital Technologies.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Redwan MaatougService de Psychiatrie Adulte de la Pitié-Salpêtrière, Institut du Cerveau (ICM), Sorbonne Université, Assistance Publique des Hôpitaux de Paris (AP-HP), Paris, France.
Antoine OudinService de Psychiatrie Adulte de la Pitié-Salpêtrière, Institut du Cerveau (ICM), Sorbonne Université, Assistance Publique des Hôpitaux de Paris (AP-HP), Paris, France.
Vladimir AdrieniCRIN (Infrastructure for Clinical Research in Neurosciences), Paris Brain Institute (ICM), Sorbonne Université, INSERM, CNRS, Paris, France.
Bertrand SaudreauiCRIN (Infrastructure for Clinical Research in Neurosciences), Paris Brain Institute (ICM), Sorbonne Université, INSERM, CNRS, Paris, France.
Olivier BonnotCHU de Nantes, Department of Child and Adolescent Psychiatry, Nantes, France.
Bruno MilletService de Psychiatrie Adulte de la Pitié-Salpêtrière, Institut du Cerveau (ICM), Sorbonne Université, Assistance Publique des Hôpitaux de Paris (AP-HP), Paris, France.
Florian FerreriiCRIN (Infrastructure for Clinical Research in Neurosciences), Paris Brain Institute (ICM), Sorbonne Université, INSERM, CNRS, Paris, France.
Stephane MouchabaciCRIN (Infrastructure for Clinical Research in Neurosciences), Paris Brain Institute (ICM), Sorbonne Université, INSERM, CNRS, Paris, France.
Alexis BourlaiCRIN (Infrastructure for Clinical Research in Neurosciences), Paris Brain Institute (ICM), Sorbonne Université, INSERM, CNRS, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mood disorders are commonly diagnosed and staged using clinical features that rely merely on subjective data. The concept of digital phenotyping is based on the idea that collecting real-time markers of human behavior allows us to determine the digital signature of a pathology. This strategy assumes that behaviors are quantifiable from data extracted and analyzed through digital sensors, wearable devices, or smartphones. That concept could bring a shift in the diagnosis of mood disorders, introducing for the first time additional examinations on psychiatric routine care. Objective: The main objective of this review was to propose a conceptual and critical review of the literature regarding the theoretical and technical principles of the digital phenotypes applied to mood disorders. Methods: We conducted a review of the literature by updating a previous article and querying the PubMed database between February 2017 and November 2021 on titles with relevant keywords regarding digital phenotyping, mood disorders and artificial intelligence. Results: Out of 884 articles included for evaluation, 45 articles were taken into account and classified by data source (multimodal, actigraphy, ECG, smartphone use, voice analysis, or body temperature). For depressive episodes, the main finding is a decrease in terms of functional and biological parameters [decrease in activities and walking, decrease in the number of calls and SMS messages, decrease in temperature and heart rate variability (HRV)], while the manic phase produces the reverse phenomenon (increase in activities, number of calls and HRV). Conclusion: The various studies presented support the potential interest in digital phenotyping to computerize the clinical characteristics of mood disorders.

Indexed as

artificial intelligencebipolar disorderdepressive disorderdigital phenotypingmachine learningmood disorders

Identifiers

PMID35958638
PMCPMC9360315

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.