Evidence map›Paper›PMID 35958497›Full record

ArticleAmerican journal of translational research2022

Arsenic exposure increases susceptibility to

Fan Yang, Zhenya Tan, Yuanjuan Dai, Xingxing Wang, Zhen Huang, Chen Kan, Siying Wang

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Fan YangDepartment of Pathophysiology, School of Basic Medical Sciences, Anhui Medical University Hefei, Anhui, China.
Zhenya TanDepartment of Pathophysiology, School of Basic Medical Sciences, Anhui Medical University Hefei, Anhui, China.
Yuanjuan DaiDepartment of Pathophysiology, School of Basic Medical Sciences, Anhui Medical University Hefei, Anhui, China.
Xingxing WangDepartment of Pathophysiology, School of Basic Medical Sciences, Anhui Medical University Hefei, Anhui, China.
Zhen HuangDepartment of Pathophysiology, School of Basic Medical Sciences, Anhui Medical University Hefei, Anhui, China.
Chen KanDepartment of Pathophysiology, School of Basic Medical Sciences, Anhui Medical University Hefei, Anhui, China.
Siying WangDepartment of Pathophysiology, School of Basic Medical Sciences, Anhui Medical University Hefei, Anhui, China.
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the synergistic effect and metabolic mechanism of chronic arsenic exposure and

methodsArsenic-transformed

resultsLow-dose arsenic exposure promoted WT MEFs proliferation and exacerbated malignancy driven by

conclusionThis study found that metabolic reprogramming, particularly mitochondrial hyperactivation, is a core mechanism underlying tumorigenesis induced by the synergistic effect of

Indexed as

Arsenicmitochondrial hypermetabolismmTORPTPN11

Identifiers

PMID35958497
PMCPMC9360862
OpenAlexW4291708451

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.