ArticleAmerican journal of translational research2022
Global research hotspots and trends of the Notch signaling pathway in the field of cancer: a bibliometric study.
Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- A scientometric study on Wnt and Notch signaling pathways in oral potentially malignant disorders and oral cancer.Journal of dental sciences · 2025Article
- Article
- Bibliometric Analysis of Research Relating to Perineal Pain Reported over the Period 1981 to 2021.Journal of personalized medicine · 2023Article
- Global characteristics and trends of presbycusis research from 2002 to 2021: a bibliometric study.American journal of translational research · 2023Article
- Characterization of global research hotspots and trends on ten-eleven translocation 2: visualization and bibliometric analysis.American journal of translational research · 2022Article
- Research hotspots and trends in virtual reality combined exercise therapy for stroke rehabilitation: A bibliometric analysis.Digital healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo analyze the development status, research hotspots, research frontiers and future development trends of the Notch signaling pathway in cancer through bibliometric analysis.
methodsPublications related to the Notch signaling pathway in cancer were obtained from the Web of Science Core Collection (WoSCC), and information was extracted from the articles using Microsoft Excel 2020, CiteSpace V and VOSviewer software for visual analysis.
resultsThe country and institution with the most publications are the USA and Harvard University, respectively. PLoS One is the most published journal, and Cancer Research is the most cocited journal. The author with the most published articles was L Miele, and the most cocited author was ZW Wang. The top 3 keywords were activation, differentiation and growth. Metastasis, epithelial-mesenchymal transition (EMT), invasion, target and resistance are the current research hotspots and frontiers in this field.
conclusionsResearch related to the Notch signaling pathway in cancer is currently booming, and the USA has made the greatest contribution to this field. At present, the research hotspots and research frontiers in this field mainly focus on the regulatory role of the Notch signaling pathway in tumor invasion and metastasis, the regulation of the Notch signaling pathway in tumor progression through EMT, and the participation of the Notch signaling pathway in the regulation of chemotherapy or immunotherapy resistance to tumors.
Indexed as
Identifiers
35958476PMC9360898W4291708929What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.