Evidence map›Paper›PMID 35958436›Full record

ArticleJournal of the Endocrine Society2022

Hepatic Steatosis and High-Normal Fasting Glucose as Risk Factors for Incident Prediabetes.

Toru Aizawa, Yasuto Nakasone, Norimitsu Murai, Rie Oka, Shoichiro Nagasaka, Koh Yamashita, Takahiro Sakuma, Kendo Kiyosawa

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Toru AizawaDiabetes Center, Aizawa Hospital, Matsumoto 390-8510, Japan.ORCID https://orcid.org/0000-0003-4653-3681
Yasuto NakasoneDiabetes Center, Aizawa Hospital, Matsumoto 390-8510, Japan.
Norimitsu MuraiDivision of Diabetes, Metabolism and Endocrinology, Showa University Fujigaoka Hospital, Yokohama 227-8501, Japan.
Rie OkaDepartment of Internal Medicine, Hokuriku Central Hospital, Toyama 932-8503, Japan.
Shoichiro NagasakaDivision of Diabetes, Metabolism and Endocrinology, Showa University Fujigaoka Hospital, Yokohama 227-8501, Japan.
Koh YamashitaDiabetes Center, Aizawa Hospital, Matsumoto 390-8510, Japan.
Takahiro SakumaDepartment of Internal Medicine, Ina Central Hospital, Ina 396-8555, Japan.
Kendo KiyosawaDepartment of Gastroenterology, Aizawa Hospital, Matsumoto 390-8510, Japan.
Aizawa Hospital · JPShowa University Fujigaoka Hospital · JPHokuriku Electric Power Company (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Context: The role of hepatic steatosis (HS) in the initial stages of developing type 2 diabetes remains unclear. Objective: We aimed to clarify the impact of HS indexed by Fatty Liver Index (FLI) and high-normal fasting plasma glucose (FPG) as risk factors for incident prediabetes in a nonobese cohort. Methods: Data from 1125 participants with ADA-defined normal glucose metabolism (median age 52 years; BMI 23.1 kg/m Results: In the entire population, FLI was positively correlated with FPG ( Conclusion: Even among nonobese individuals, HS indexed by FLI and a high-normal FPG (≥ 5.3 mmol/L) are risk factors for prediabetes, independently from insulin.

Indexed as

fasting plasma glucosehepatic steatosisinsulin secretioninsulin sensitivityprediabetes

Identifiers

PMID35958436
PMCPMC9359444
OpenAlexW4289048674

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.