Evidence map›Paper›PMID 35958343›Full record

ArticleTranslational lung cancer research2022

Anti-Zic4 paraneoplastic cerebellar degeneration in a patient with EGFR-mutated NSCLC: a case report.

Javier Pozas, Víctor Albarrán-Fernández, Luis González-Campo, María Eugenia Olmedo-García, Elena Corral de la Fuente, Iñigo Corral-Corral, Ángela Carrasco, Teresa Alonso-Gordoa, Javier Molina-Cerrillo, Yolanda Lage-Alfranca and 2 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Translational lung cancer research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Javier Pozas *Department of Medical Oncology, Ramón y Cajal University Hospital, Madrid, Spain.
Víctor Albarrán-Fernández *Department of Medical Oncology, Ramón y Cajal University Hospital, Madrid, Spain.
Luis González-CampoDepartment of Radiology, Ramón y Cajal University Hospital, Madrid, Spain.
María Eugenia Olmedo-GarcíaDepartment of Medical Oncology, Ramón y Cajal University Hospital, Madrid, Spain.
Elena Corral de la FuenteEarly Phase Clinical Drug Development in Oncology, South Texas Accelerated Research Therapeutics (START), Centro Integral Oncológico Clara Campal (CIOCC), Madrid, Spain.
Iñigo Corral-CorralDepartment of Neurology, Ramón y Cajal University Hospital, Madrid, Spain.
Ángela CarrascoDepartment of Immunology, Ramón y Cajal University Hospital, Madrid, Spain.
Teresa Alonso-GordoaDepartment of Medical Oncology, Ramón y Cajal University Hospital, Madrid, Spain.
Javier Molina-CerrilloDepartment of Medical Oncology, Ramón y Cajal University Hospital, Madrid, Spain.
Yolanda Lage-AlfrancaDepartment of Medical Oncology, Ramón y Cajal University Hospital, Madrid, Spain.
Ana Gómez-RuedaDepartment of Medical Oncology, Ramón y Cajal University Hospital, Madrid, Spain.
Pilar GarridoDepartment of Medical Oncology, Ramón y Cajal University Hospital, Madrid, Spain.
Instituto Cajal · ESSouth Texas Accelerated Research Therapeutics · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paraneoplastic cerebellar degeneration (PCD) is one of the most prevalent neurological paraneoplastic syndromes, typically associated with small cell lung cancer (SCLC). PCD is thought to be caused by proteins expressed by tumor cells which trigger an antibody-mediated immune response. Despite PCD being commonly associated with anti-Yo, anti-Hu and anti-Tr/DNER antibodies, PCD is the most prevalent paraneoplastic syndrome in patients harboring anti-Zic4 antibodies. We report what, to our knowledge, is the first known case of anti-Zic4 mediated PCD in a patient with

Indexed as

anti-Zic4 antibodiescase reportEGFRnon-small cell lung cancer (NSCLC)Paraneoplastic cerebellar degeneration (PCD)

Identifiers

PMID35958343
PMCPMC9359961
OpenAlexW4285531551

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.