Evidence map›Paper›PMID 35958118›Full record

ArticleMetabolism open2022

Therapeutic effects of aqueous extract of bioactive active component of

Sunday Aderemi Adelakun, Victor Okoliko Ukwenya, Akwu Bala Peter, Adewale Jacob Siyanbade, Comfort Oluwakorede Akinwumiju

Open access · goldAbstract read
In one paragraph

Article in Metabolism open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Chitosan/Alginate-LoadedReproductive medicine and biology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sunday Aderemi AdelakunDepartment of Human Anatomy, College of Health Sciences, Federal University of Technology, Akure, Nigeria.
Victor Okoliko UkwenyaDepartment of Human Anatomy, College of Health Sciences, Federal University of Technology, Akure, Nigeria.
Akwu Bala PeterDepartment of Anatomy, Kogi State University, Anyigba, Nigeria.
Adewale Jacob SiyanbadeDepartment of Anatomy, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.
Comfort Oluwakorede AkinwumijuDepartment of Human Anatomy, College of Health Sciences, Federal University of Technology, Akure, Nigeria.
Federal University of Technology · NGKogi State University · NGLadoke Akintola University of Technology · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Polycystic ovary syndrome (PCOS) is an endocrine disorder, affecting women of reproductive age. Methods: Female rats were randomized into four groups (n = 6). Group A control received 2 ml distilled water. Group B received a single dose of 4 mg/kg body weight (bwt) i.p estradiol valerate (EV). Group C received 500 mg/kg bwt AGC and group D received a single dose of 4 mg/kg bwt i.p EV followed by 500 mg/kg bwt AGC orally for 30 days. Parameters tested include follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T), estradiol (E2), progesterone (P), C-reactive protein (CRP), interleukin (IL)-6, IL-18 and tumor necrosis factor (TNF)- α, malondialdehyde (MDA), superoxide dismutase (SOD), Catalase (CAT), total protein (TP), total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and ovary and uterus histomorphometric. Results: Conclusion:

Indexed as

Ageratum conyzoidesEstradiol valerateOvaryPolycystic ovarian syndromeUterus

Identifiers

PMID35958118
PMCPMC9361322
OpenAlexW4286253113

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.