Evidence map›Paper›PMID 35957921›Full record

ArticleFrontiers in behavioral neuroscience2022

Aversive Pavlovian inhibition in adult attention-deficit/hyperactivity disorder and its restoration by mindfulness-based cognitive therapy.

Dirk E M Geurts, Hanneke E M den Ouden, Lotte Janssen, Jennifer C Swart, Monja I Froböse, Roshan Cools, Anne E M Speckens

Open access · goldAbstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Dirk E M GeurtsDonders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands.
Hanneke E M den OudenDonders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands.
Lotte JanssenDepartment of Psychiatry, Radboud University Medical Centre, Nijmegen, Netherlands.
Jennifer C SwartDonders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands.
Monja I FroböseInstitute of Experimental Psychology, Heinrich Heine University of Düsseldorf, Düsseldorf, Germany.
Roshan CoolsDonders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands.
Anne E M SpeckensDepartment of Psychiatry, Radboud University Medical Centre, Nijmegen, Netherlands.
Radboud University Nijmegen · NLHeinrich Heine University Düsseldorf · DERadboud University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Control over the tendency to make or withhold responses guided by contextual Pavlovian information plays a key role in understanding impulsivity and hyperactivity. Here we set out to assess (1) the understudied relation between contextual Pavlovian inhibitory control and hyperactivity/impulsivity in adults with ADHD and (2) whether this inhibition can be enhanced by mindfulness based cognitive therapy (MBCT). Methods: Within the framework of a randomized controlled trial 50 Adult ADHD patients were assessed before and after 8 weeks of treatment as usual (TAU) with ( Results: Task results revealed (1) less aversive Pavlovian inhibition in ADHD patients with clinically relevant hyperactivity/impulsivity than in those without; and (2) enhanced Pavlovian inhibition across all ADHD patients after TAU+MBCT compared with TAU. Conclusion: These findings offer new insights in the neurocognitive mechanisms of hyperactivity/impulsivity in ADHD and its treatment: We reveal a role for Pavlovian inhibitory mechanisms in understanding hyperactive/impulsive behaviors in ADHD and point toward MBCT as an intervention that might influence these mechanisms.

Indexed as

ADHDimpulsivityinhibitionmindfulness based cognitive therapyPavlovian to instrumental transfer

Identifiers

PMID35957921
PMCPMC9359138
OpenAlexW4287447923

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.