Evidence map›Paper›PMID 35957832›Full record

ArticleFrontiers in endocrinology2022

Yongqiang Ma, Guangshun Chen, Junfang Yi, Qiang Li, Zhi Tan, Wenling Fan, Xiaohua Luo, Zhiyong He, Zhongzhou Si, Jiequn Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yongqiang MaDepartment of Liver Transplant, The Second Xiangya Hospital of Central South University, Changsha, China.
Guangshun ChenDepartment of Liver Transplant, The Second Xiangya Hospital of Central South University, Changsha, China.
Junfang YiDepartment of Liver Transplant, The Second Xiangya Hospital of Central South University, Changsha, China.
Qiang LiDepartment of Liver Transplant, The Second Xiangya Hospital of Central South University, Changsha, China.
Zhi TanDepartment of Gastroenterology, The First Hospital of Changsha, Changsha, China.
Wenling FanDepartment of Gastroenterology, The First Hospital of Changsha, Changsha, China.
Xiaohua LuoDepartment of Liver Transplant, The Second Xiangya Hospital of Central South University, Changsha, China.
Zhiyong HeDepartment of Liver Transplant, The Second Xiangya Hospital of Central South University, Changsha, China.
Zhongzhou SiDepartment of Liver Transplant, The Second Xiangya Hospital of Central South University, Changsha, China.
Jiequn LiDepartment of Liver Transplant, The Second Xiangya Hospital of Central South University, Changsha, China.
Second Xiangya Hospital of Central South University · CNCentral South University · CNThe First Hospital of Changsha · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic-associated fatty liver disease (MAFLD) affects approximately a quarter of the global population. Identification of the key genes and pathways involved in hepatic lipid metabolism is of the utmost importance for the diagnosis, treatment, and prevention of MAFLD. In this study, differentially expressed genes were identified through whole-genome transcriptional analysis of liver tissue from MAFLD patients and healthy controls, and a series of lipid metabolism-related molecules and pathways were obtained through pathway analysis. Subsequently, we focused on Iroquois homeobox protein 3 (

Indexed as

Homeodomain ProteinsLipid MetabolismLiverNon-alcoholic Fatty Liver DiseaseTranscription FactorsCholesterolHumansCholesterolHomeodomain ProteinsIRX3 protein, humanTranscription Factorsdifferentially expressed genesIRX3lipid metabolismMAFLDmitochondrion

Identifiers

PMID35957832
PMCPMC9360787
OpenAlexW4288038775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.