Evidence map›Paper›PMID 35957130›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Fabrication of Nylon-6 and Nylon-11 Nanoplastics and Evaluation in Mammalian Cells.

Sai Archana Krovi, Maria M Moreno Caffaro, Shyam Aravamudhan, Ninell P Mortensen, Leah M Johnson

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. A genetic tool to express long fungal biosynthetic genes.Fungal biology and biotechnology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sai Archana KroviRTI International, 3040 E. Cornwallis Drive, Research Triangle Park, Durham, NC 27709, USA.ORCID 0000-0003-1546-9955
Maria M Moreno CaffaroRTI International, 3040 E. Cornwallis Drive, Research Triangle Park, Durham, NC 27709, USA.
Shyam AravamudhanJoint School of Nanoscience and Nanoengineering, North Carolina A&T State University, 2907 E. Gate City Blvd., Greensboro, NC 27401, USA.ORCID 0000-0001-9968-7188
Ninell P MortensenRTI International, 3040 E. Cornwallis Drive, Research Triangle Park, Durham, NC 27709, USA.
Leah M JohnsonRTI International, 3040 E. Cornwallis Drive, Research Triangle Park, Durham, NC 27709, USA.
RTI International · USNorth Carolina Agricultural and Technical State University · US

Funding

National Science Foundation ECCS- 2025462RTI International 0272200.016
6 · The paper itself

Abstract

Microplastics (MPs) and nanoplastics (NPs) exist in certain environments, beverages, and food products. However, the ultimate risk and consequences of MPs and NPs on human health remain largely unknown. Studies involving the biological effects of small-scale plastics have predominantly used commercially available polystyrene beads, which cannot represent the breadth of globally dominant plastics. Nylon is a commodity plastic that is used across various industry sectors with substantial global production. Here, a series of well-characterized nylon-11 and nylon-6 NPs were successfully fabricated with size distributions of approximately 100 nm and 500 nm, respectively. The facile fabrication steps enabled the incorporation of fluorescent tracers in these NPs to aid the intracellular tracking of particles. RAW 264.7 macrophages were exposed to nylon NPs in a dose-dependent manner and cytotoxic concentrations and cellular uptake were determined. These well-characterized nylon NPs support future steps to assess how the composition and physicochemical properties may affect complex biological systems and ultimately human health.

Indexed as

microplasticsnanoplasticsnanoplastics cellular responsenanoplastics fabricationnylon

Identifiers

PMID35957130
PMCPMC9370135
OpenAlexW4292451762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.