Evidence map›Paper›PMID 35956988›Full record

ArticleMolecules (Basel, Switzerland)2022

Dihydroxyquingdainone Induces Apoptosis in Leukaemia and Lymphoma Cells via the Mitochondrial Pathway in a Bcl-2- and Caspase-3-Dependent Manner and Overcomes Resistance to Cytostatic Drugs In Vitro.

Jennifer Baas, Sebastian Bieringer, Corazon Frias, Jerico Frias, Carolina Soehnchen, Corinna Urmann, Steffi Ritter, Herbert Riepl, Aram Prokop

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Chemistry and Biological Activity of 11Molecules (Basel, Switzerland) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jennifer BaasDepartment of Pediatric Hematology/Oncology, Helios Clinic Schwerin, Wismarsche Straße 393-397, 19055 Schwerin, Germany.
Sebastian BieringerOrganic-Analytical Chemistry, Weihenstephan-Triesdorf University of Applied Sciences, 94315 Straubing, Germany.
Corazon FriasDepartment of Pediatric Hematology/Oncology, Helios Clinic Schwerin, Wismarsche Straße 393-397, 19055 Schwerin, Germany.
Jerico FriasDepartment of Pediatric Hematology/Oncology, Helios Clinic Schwerin, Wismarsche Straße 393-397, 19055 Schwerin, Germany.
Carolina SoehnchenMedical School Hamburg (MSH), University of Applied Sciences and Medical University, Am Kaiserkai 1, 20457 Hamburg, Germany.
Corinna UrmannOrganic-Analytical Chemistry, Weihenstephan-Triesdorf University of Applied Sciences, 94315 Straubing, Germany.ORCID 0000-0001-8895-9416
Steffi RitterOrganic-Analytical Chemistry, Weihenstephan-Triesdorf University of Applied Sciences, 94315 Straubing, Germany.
Herbert RieplOrganic-Analytical Chemistry, Weihenstephan-Triesdorf University of Applied Sciences, 94315 Straubing, Germany.
Aram ProkopDepartment of Pediatric Hematology/Oncology, Helios Clinic Schwerin, Wismarsche Straße 393-397, 19055 Schwerin, Germany.
Weihenstephan-Triesdorf University of Applied Sciences · DEHelios Hospital Schwerin · DEMSH Medical School Hamburg – University of Applied Sciences and Medical University · DE

Funding

Dr. Kleist Stiftung (Berlin), the Stiftung David (Köln) and the Blankenheimerdorf e.V. (Eifel) x
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cytostatic AgentsLeukemiaLymphomaApoptosisCaspase 3Indigo CarminePlant LeavesCaspase 3Cytostatic AgentsIndigo CarmineBJABintrinsic apoptosis pathwayIsatis tinctoriaNalm-6quingdainonetryptanthrin

Identifiers

PMID35956988
PMCPMC9370279
OpenAlexW4292452155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.