Evidence map›Paper›PMID 35956911›Full record

ReviewMolecules (Basel, Switzerland)2022

Neuroprotection of Cannabidiol, Its Synthetic Derivatives and Combination Preparations against Microglia-Mediated Neuroinflammation in Neurological Disorders.

Muhammad Yousaf, Dennis Chang, Yang Liu, Tianqing Liu, Xian Zhou

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

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  19. The Neurotherapeutic Arsenal inMolecules (Basel, Switzerland) · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Muhammad YousafDepartment of Bioinformatics and Biotechnology, Government College University Faisalabad, Faisalabad 38000, Pakistan.
Dennis ChangNICM Health Research Institute, Western Sydney University, Westmead, NSW 2145, Australia.
Yang LiuNICM Health Research Institute, Western Sydney University, Westmead, NSW 2145, Australia.ORCID 0000-0003-1037-4033
Tianqing LiuNICM Health Research Institute, Western Sydney University, Westmead, NSW 2145, Australia.ORCID 0000-0002-9058-2643
Xian ZhouNICM Health Research Institute, Western Sydney University, Westmead, NSW 2145, Australia.ORCID 0000-0001-8766-8158
Western Sydney University · AUGovernment College University, Faisalabad · PK

Funding

National Health and Medical Research Council 1112258
6 · The paper itself

Abstract

The lack of effective treatment for neurological disorders has encouraged the search for novel therapeutic strategies. Remarkably, neuroinflammation provoked by the activated microglia is emerging as an important therapeutic target for neurological dysfunction in the central nervous system. In the pathological context, the hyperactivation of microglia leads to neuroinflammation through the release of neurotoxic molecules, such as reactive oxygen species, proteinases, proinflammatory cytokines and chemokines. Cannabidiol (CBD) is a major pharmacologically active phytocannabinoids derived from

Indexed as

CannabidiolNervous System DiseasesHumansMicrogliaNeuroinflammatory DiseasesNeuroprotectionCannabidiolcannabidiolcannabidiol derivativesmicroglianeuroinflammationneurological disordersneuroprotection

Identifiers

PMID35956911
PMCPMC9370304
OpenAlexW4289942975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.