Evidence map›Paper›PMID 35956786›Full record

ArticleMolecules (Basel, Switzerland)2022

Muhammed Ashiq Thalappil, Elena Butturini, Alessandra Carcereri de Prati, Ilaria Bettin, Lorenzo Antonini, Filippo Umberto Sapienza, Stefania Garzoli, Rino Ragno, Sofia Mariotto

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Antioxidant Activity of Essential Oils from Pinaceae Species.Antioxidants (Basel, Switzerland) · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Muhammed Ashiq ThalappilDepartment of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, 37134 Verona, Italy.ORCID 0000-0002-1305-9453
Elena ButturiniDepartment of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, 37134 Verona, Italy.
Alessandra Carcereri de PratiDepartment of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, 37134 Verona, Italy.
Ilaria BettinDepartment of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, 37134 Verona, Italy.
Lorenzo AntoniniDepartment of Drug Chemistry and Technology, Rome Center for Molecular Design, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-3662-9241
Filippo Umberto SapienzaDepartment of Drug Chemistry and Technology, Rome Center for Molecular Design, Sapienza University of Rome, 00185 Rome, Italy.
Stefania GarzoliDepartment of Drug Chemistry and Technology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-8535-0533
Rino RagnoDepartment of Drug Chemistry and Technology, Rome Center for Molecular Design, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-5399-975X
Sofia MariottoDepartment of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, 37134 Verona, Italy.
University of Verona · ITSapienza University of Rome · IT

Funding

Sapienza University of Rome RM11916B8876093E, RM120172B8EB30C5, RM12117A89F5B8BB
6 · The paper itself

Abstract

Essential oils (EOs) and their components have been reported to possess anticancer properties and to increase the sensitivity of cancer cells to chemotherapy. The aim of this work was to select EOs able to downregulate STAT3 signaling using Western blot and RT-PCR analyses. The molecular mechanism of anti-STAT3 activity was evaluated through spectrophotometric and fluorometric analyses, and the biological effect of STAT3 inhibition was analyzed by flow cytometry and wound healing assay. Herein,

Indexed as

Antineoplastic AgentsOils, VolatilePinusPlant OilsProstatic NeoplasmsSTAT3 Transcription FactorApoptosisCell Line, TumorCell ProliferationGlutathioneHumansMaleOxidative StressReactive Oxygen SpeciesAntineoplastic AgentsGlutathioneOils, VolatilePlant OilsReactive Oxygen SpeciesSTAT3 protein, humanSTAT3 Transcription Factorapoptosisessential oiloxidative stressSTAT3

Identifiers

PMID35956786
PMCPMC9369512
OpenAlexW4288720508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.