Evidence map›Paper›PMID 35956658›Full record

ArticlePolymers2022

DEAE-Dextran Coated AgNPs: A Highly Blendable Nanofiller Enhances Compressive Strength of Dental Resin Composites.

Shabia Azhar, Nosheen Fatima Rana, Amer Sohail Kashif, Tahreem Tanweer, Iqra Shafique, Farid Menaa

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Shabia AzharDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.
Nosheen Fatima RanaDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.ORCID 0000-0002-3855-0468
Amer Sohail KashifDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.
Tahreem TanweerDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.
Iqra ShafiqueDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.
Farid MenaaDepartments of Internal Medicine and Nanomedicine, California Innovations Corporation, San Diego, CA 92037, USA.ORCID 0000-0002-0258-7322
National University of Sciences and Technology · PKCalifornia Medical Innovations Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micro-crack formation and resultant bacterial infiltration are major causes of secondary caries formation in dental resin-based composite restorations. Improving dental resin composites’ mechanical and biological properties using highly bendable nanoparticles (NPs) can resolve this issue. This study aims to develop novel Diethylaminoethyl (DEAE)-Dextran silver nanoparticles (AgNPs) and subsequently modify composite resins with these NPs to enhance their mechanical and antibacterial properties. DEAE-Dextran AgNPs were successfully synthesized using a chemical reduction method that was confirmed with the help of ultraviolet-visible (UV-Vis) spectroscopy, scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), Zeta potential, and energy-dispersive X-ray spectroscopy (EDS). Antibacterial activity of a composite disc with DEAE-Dextran AgNPs was tested against Streptococcus mutans, Enterococcus faecalis, and oral microcosm. The composite discs prepared with DEAE-Dextran AgNPs exhibited excellent antibacterial activity compared with composite resin reinforced by simple AgNPs (p < 0.05). Mechanical properties were significantly enhanced by adding DEAE-Dextran into composite resin (p < 0.05). Moreover, unlike AgNPs, DEAE-Dextran AgNPs were found to be less hemolytic. The results establish strong ground applications for DEAE-Dextran-modified dental composite resins in restorative dental applications.

Indexed as

antibacterial activitydental compositemechanical strengthnanoparticles

Identifiers

PMID35956658
PMCPMC9371126
OpenAlexW4289524680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.