Evidence map›Paper›PMID 35956323›Full record

ArticleNutrients2022

Vitamin D, Vitamin D-Binding Proteins, and VDR Polymorphisms in Individuals with Hyperglycaemia.

Rajiv Erasmus, Setjie Maepa, Ian Machingura, Saarah Davids, Shanel Raghubeer, Tandi Matsha

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Oman medical journal · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rajiv ErasmusDepartment of Pathology, Chemical Pathology Division, National Health Laboratory Service (NHLS) and Stellenbosch University, Tygerberg Hospital, Cape Town 7505, South Africa.ORCID 0000-0001-6831-4215
Setjie MaepaDepartment of Pathology, Chemical Pathology Division, National Health Laboratory Service (NHLS) and Stellenbosch University, Tygerberg Hospital, Cape Town 7505, South Africa.ORCID 0000-0003-2881-5167
Ian MachinguraSAMRC/CPUT/Cardiometabolic Health Research Unit, Department of Biomedical Science, Faculty of Health & Wellness Sciences, Cape Peninsula University of Technology, Cape Town 7530, South Africa.
Saarah DavidsSAMRC/CPUT/Cardiometabolic Health Research Unit, Department of Biomedical Science, Faculty of Health & Wellness Sciences, Cape Peninsula University of Technology, Cape Town 7530, South Africa.
Shanel RaghubeerSAMRC/CPUT/Cardiometabolic Health Research Unit, Department of Biomedical Science, Faculty of Health & Wellness Sciences, Cape Peninsula University of Technology, Cape Town 7530, South Africa.ORCID 0000-0002-8161-5458
Tandi MatshaSAMRC/CPUT/Cardiometabolic Health Research Unit, Department of Biomedical Science, Faculty of Health & Wellness Sciences, Cape Peninsula University of Technology, Cape Town 7530, South Africa.ORCID 0000-0001-5251-030X
South African Medical Research Council · ZANational Health Laboratory Service · ZA

Funding

South African Medical Research Council MRC-RFA-UFSP-01-2013/VMH StudySouth African National Research Foundation Grant no. 115450
6 · The paper itself

Abstract

Vitamin D reportedly plays an important role in the pathogenesis of diabetes mellitus; however, this role is unclear and debated. This study investigated the association between 25(OH) vitamin D, vitamin D-binding proteins, and vitamin D receptor (VDR) polymorphisms in healthy individuals and those with prediabetes and type 2 diabetes mellitus (T2D) from South Africa. A cross-sectional study was conducted involving subjects of mixed ancestry aged ≥20 years. Males presented with higher mean 25(OH) vitamin D levels than females, while females exhibited significantly higher serum vitamin D-binding protein levels. Significant differences in mean 25(OH) vitamin D levels were observed in normo-glycaemic, prediabetes, screen-detected DM, and known DM individuals. Vitamin D receptor SNPs

Indexed as

Diabetes Mellitus, Type 2HyperglycemiaPrediabetic StateVitamin D DeficiencyCase-Control StudiesCross-Sectional StudiesFemaleHumansMalePolymorphism, Single NucleotideReceptors, CalcitriolVitamin DVitamin D-Binding ProteinVitaminsReceptors, CalcitriolVDR protein, humanVitamin DVitamin D-Binding ProteinVitaminshyperglycaemiaSouth Africavitamin Dvitamin D-binding proteinvitamin D receptor

Identifiers

PMID35956323
PMCPMC9370481
OpenAlexW4289204836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.